PMID: 30173240Sep 3, 2018Paper

Primary uterine angiosarcoma with "rhabdoid morphology": A case report

The Malaysian Journal of Pathology
J S GandhiN Seth

Abstract

Primary uterine angiosarcoma is a very rare tumour, with only 23 cases described till now. It is a malignant tumour with cells variably recapitulating the morphologic features of an endothelium and expressing immunohistochemical markers of endothelial cells. In general, it is a bulky neoplasm and frequently is at advance stage of disease at presentation. In general, patients with uterine angiosarcoma tend to have a poorer prognosis, mostly related to the aggressive nature and the metastatic potential of these tumours. We report a rare case of primary uterine angiosarcoma with unusual rhabdoid morphology in a 41-year-old female, who underwent radical hysterectomy and died of disease after 4 months of treatment. We described the differential diagnosis of primary angiosarcoma of the uterus that can pose a diagnostic challenge.

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