PMID: 9545136Apr 17, 1998Paper

Primitive neuroectodermal tumor in a two-month-old black and white Colobus monkey

Veterinary Pathology
P H LongK N Cameron

Abstract

A 2-month-old male black and white Colobus monkey (Colobus guereza kikuyuensis) was euthanatized because of progressive physical deterioration, rear limb paralysis, lymphadenopathy, and the presence of facial and retroperitoneal lumbar masses. At necropsy, soft white masses were present in and around lumbar vertebrae, the subcutis of the face, multiple lymph nodes, and the fourth ventricle of the brain. Histologic and immunohistochemical analysis of these masses revealed a primitive neoplasm with both neuronal and glial differentiation, consistent with a primitive neuroectodermal tumor (PNET) with bipotential differentiation. The extracranial tumors were synaptophysin (SYN)-positive, glial fibrillary acidic protein (GFAP)-negative, and neurofilament protein (NFP)-negative, while the intracranial tumor was SYN-positive, GFAP-positive, and NFP-negative.

References

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Jul 1, 1993·Brain Pathology·P KleihuesB W Scheithauer

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Citations

Aug 4, 1999·Journal of Medical Primatology·E H JohnsonD E Muirhead
May 30, 2013·Journal of Comparative Pathology·J JungingerF Seehusen
Aug 25, 2011·Journal of Comparative Pathology·S KleinschmidtP Wohlsein
Dec 19, 2008·Journal of Comparative Pathology·S A HeadleyA Sukura
Nov 11, 2011·Journal of Medical Primatology·Wijit BanlunaraHiroyuki Nakayama
Dec 22, 2016·Journal of the American Veterinary Medical Association·Lauren E HimmelMichael J Oglesbee
May 25, 2012·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Paul R FacemireShelley P Honnold
Jul 3, 2004·Veterinary Pathology·H E V De CockR J Higgins
Sep 12, 2018·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Brittany McHaleDaniel R Rissi
Oct 6, 2019·Journal of Veterinary Diagnostic Investigation : Official Publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·Yu-Han HsiehWen-Ta Li
Nov 17, 2019·International Journal of Molecular Sciences·Jana SchneiderMartin S Staege

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