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Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome

Cell Reports

Oct 13, 2015

Debora FumagalliVincent Detours

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Abstract

Little is known about how RNA editing operates in cancer. Transcriptome analysis of 68 normal and cancerous breast tissues revealed that the editing enzyme ADAR acts uniformly, on the same loci, across tissues. In controlled ADAR expression experiments, the editing frequency increased a...read more

Mentioned in this Paper

Adenosine Deaminase
Malignant Neoplasm of Breast
Malignant Neoplasms
DNA
Inflammation
Interferon Type I
Interferons
Logistic Models
Neoplasms
RNA
19
160
Paper Details
References
    • References49
    • Citations31
    • References49
    • Citations31
  • Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome

    Cell Reports

    Oct 13, 2015

    Debora FumagalliVincent Detours

    PMID: 26440892

    DOI: 10.1016/j.celrep.2015.09.032

    Abstract

    Little is known about how RNA editing operates in cancer. Transcriptome analysis of 68 normal and cancerous breast tissues revealed that the editing enzyme ADAR acts uniformly, on the same loci, across tissues. In controlled ADAR expression experiments, the editing frequency increased a...read more

    Mentioned in this Paper

    Adenosine Deaminase
    Malignant Neoplasm of Breast
    Malignant Neoplasms
    DNA
    Inflammation
    19
    160
    Paper Details
    References
    • References49
    • Citations31
    • References49
    • Citations31
  • Get paper from

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