Principles of temporal association cortex organisation as revealed by connectivity gradients

Brain Structure & Function
Guilherme Blazquez FrechesRogier B Mars

Abstract

To establish the link between structure and function of any large area of the neocortex, it is helpful to identify its principles of organisation. One way to establish such principles is to investigate how differences in whole-brain connectivity are structured across the area. Here, we use Laplacian eigenmaps on diffusion MRI tractography data to investigate the organisational principles of the human temporal association cortex. We identify three overlapping gradients of connectivity that are, for the most part, consistent across hemispheres. The first gradient reveals an inferior-superior organisation of predominantly longitudinal tracts and separates visual and auditory unimodal and multimodal cortices. The second gradient radiates outward from the posterior middle temporal cortex with the arcuate fascicle as a distinguishing feature; the third gradient is concentrated in the anterior temporal lobe and emanates towards its posterior end. We describe the functional relevance of each of these gradients through the meta-analysis of data from the neuroimaging literature. Together, these results unravel the overlapping dimensions of structural organization of the human temporal cortex and provide a framework underlying its functio...Continue Reading

References

Jan 1, 1997·Annual Review of Neuroscience·S P WiseR Caminiti
Sep 2, 2004·Proceedings of the National Academy of Sciences of the United States of America·H Johansen-BergP M Matthews
Nov 24, 2004·Trends in Cognitive Sciences·Joaquín M Fuster
Apr 28, 2007·Trends in Neurosciences·Jean-Philippe Thivierge, Gary F Marcus
Oct 30, 2007·Neuron·Brian A WandellAlyssa A Brewer
Mar 18, 2008·Nature Neuroscience·James K RillingTimothy E J Behrens
Jul 16, 2008·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Marco Catani, Michel Thiebaut de Schotten
Dec 24, 2008·Brain Structure & Function·Nikos Makris, Deepak N Pandya
Feb 4, 2009·Proceedings of the National Academy of Sciences of the United States of America·C J HoneyP Hagmann
Jun 9, 2009·Nature Neuroscience·Frédérique KouneiherEtienne Koechlin
Jan 26, 2010·NeuroImage·Colin HumphriesJeffrey R Binder
Feb 6, 2010·Proceedings of the National Academy of Sciences of the United States of America·Matthew A Lambon RalphEmily J Mayberry
Jun 28, 2011·Nature Methods·Tal YarkoniTor D Wager
Feb 16, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Saad JbabdiTimothy E J Behrens
Oct 12, 2012·Social Cognitive and Affective Neuroscience·Ingrid R OlsonLars A Ross
Dec 26, 2012·Trends in Cognitive Sciences·Dwight J KravitzMortimer Mishkin
Jan 10, 2013·Current Opinion in Neurobiology·Saad JbabdiTimothy E Behrens
May 15, 2013·NeuroImage·Matthew F GlasserUNKNOWN WU-Minn HCP Consortium
May 21, 2013·NeuroImage·David C Van EssenUNKNOWN WU-Minn HCP Consortium
May 25, 2013·NeuroImage·Stamatios N SotiropoulosUNKNOWN WU-Minn HCP Consortium
Jun 12, 2013·Proceedings of the National Academy of Sciences of the United States of America·Rogier B MarsMatthew F S Rushworth
Feb 4, 2014·Neuroscience and Biobehavioral Reviews·Matthias SchurzJosef Perner
Aug 27, 2014·Current Opinion in Neurobiology·Marco Catani, Valentina Bambini
Sep 23, 2014·Journal of Cognitive Neuroscience·Robert S HurleyM-Marsel Mesulam
Apr 29, 2015·Frontiers in Neuroinformatics·Krzysztof J GorgolewskiDaniel S Margulies
Jun 9, 2015·ELife·Tobias Navarro SchröderChristian F Doeller
Jun 29, 2015·Brain and Language·Philip T Lai, Judy S Reilly
Oct 27, 2015·Annals of the New York Academy of Sciences·Grace E RiceMatthew A Lambon Ralph
Nov 7, 2015·Journal of Cognitive Neuroscience·Gorana PobricRoland Zahn
Dec 3, 2015·Brain Structure & Function·Rogier B MarsMatthew F S Rushworth
Apr 28, 2016·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Claude J BajadaLauren L Cloutman
Nov 3, 2016·Proceedings of the National Academy of Sciences of the United States of America·Daniel S MarguliesJonathan Smallwood
Nov 25, 2016·Nature Reviews. Neuroscience·Matthew A Lambon RalphTimothy T Rogers
Apr 16, 2017·NeuroImage·Claude J BajadaLauren L Cloutman
Apr 19, 2017·NeuroImage·Rebecca L JacksonMatthew A Lambon Ralph
Jul 2, 2017·NeuroImage·Koen V HaakChristian F Beckmann
Aug 15, 2017·Nature Human Behaviour·Andre F MarquandChristian F Beckmann
Dec 6, 2017·Trends in Cognitive Sciences·Julia M HuntenburgDaniel S Margulies

❮ Previous
Next ❯

Citations

May 18, 2020·Brain Structure & Function·Hiromasa Takemura, Michel Thiebaut de Schotten
Feb 4, 2021·Annual Review of Neuroscience·Rogier B MarsMatthew F S Rushworth
Apr 24, 2020·NeuroImage·Alice WaymelMichel Thiebaut de Schotten
Sep 25, 2021·Human Brain Mapping·Guilherme Blazquez FrechesRogier B Mars

❮ Previous
Next ❯

Software Mentioned

Neurovault
MR Comparative Anatomy Toolbox MrCat
XTract
BEDPOSTX
PROBTRACKX
FSL
aparc
Freesurfer

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
Katherine L BryantTodd M Preuss
Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
Claude J BajadaMatthew A Lambon Ralph
© 2021 Meta ULC. All rights reserved