Printed Colorimetric Arrays for the Identification and Quantification of Acids and Bases

Analytical Chemistry
Michael J KangasAndrea E Holmes

Abstract

Solid supported colorimetric sensing arrays have the advantage of portability and ease of use when deployed in the field, such as crime scenes, disaster zones, or in war zones, but many sensor arrays require complex fabrication methods. Here, we report a practical method for the fabrication of 4 × 4 colorimetric sensor arrays, which are printed on nylon membranes, using a commercially available inkjet printer. In order to test the efficacy of the printed arrays, they were exposed to 43 analytes at concentrations ranging from 0.001 to 3.0 M for a total of 559 samples of inorganic and organic acids or bases including hydrochloric, acetic, phthalic, malonic, picric, and trifluoroacetic acid, ammonium hydroxide, sodium hydroxide, lysine, and water as the control. Colorimetric data from the imaged arrays was analyzed with linear discriminant analysis and k-nearest neighbors to determine the analyte and concentration with ∼88-90% accuracy. Overall, the arrays have impressive analytical power to identify a variety of analytes at different concentrations while being simple to fabricate.

References

Nov 28, 2006·Journal of Chemical Information and Modeling·Florian NigschJohn B O Mitchell
Oct 28, 2008·Langmuir : the ACS Journal of Surfaces and Colloids·Jin Ho BangKenneth S Suslick
May 23, 2009·The Journal of Organic Chemistry·Masanori KitamuraEric V Anslyn
Feb 18, 2010·Nature Chemistry·Sung H LimKenneth S Suslick
Aug 30, 2012·Nature Methods·Caroline A SchneiderKevin W Eliceiri
Sep 8, 2012·Chemical Communications : Chem Comm·Katherine ChulviJosé-L Vivancos
May 17, 2013·Analytical and Bioanalytical Chemistry·Nobutoshi KomuroDaniel Citterio
Oct 5, 2013·Chemical Society Reviews·Jon R AskimKenneth S Suslick
Jan 11, 2014·Journal of Sensor Technology·Hannah JohnkeSharmin Sikich
Jul 16, 2014·Journal of Sensor Technology·Gary BatresSharmin Sikich
Jul 16, 2015·Analytical Chemistry·Jon R Askim, Kenneth S Suslick
Nov 10, 2015·Analytica Chimica Acta·Luis Fermín Capitán-VallveyAlberto J Palma
Sep 17, 2016·Critical Reviews in Analytical Chemistry·Michael J KangasAndrea E Holmes
May 26, 2018·Journal of Chemometrics·Michael J KangasAndrea E Holmes
Jan 1, 2018·International Journal of Chemistry·Michael James KangasAndrea E Holmes

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