Prior adverse pregnancy outcome and the risk of stillbirth

Obstetrics and Gynecology
Svein RasmussenKari Klungsøyr Melve


To estimate whether a history of fetal growth restriction, abruptio placentae, preeclampsia, or live preterm birth is associated with excess risk of stillbirth in a subsequent pregnancy. We also estimated the maternal and paternal contributions to such effects. This was a population-based cohort study from 1967 to 2005. Pairs of first and second, second and third, third and fourth, and fourth and fifth births were identified among all births from the Medical Birth Registry of Norway; 747,221 pairs with the same parents, 51,708 with the same mother and different father, and 65,602 with the same father and different mother. The associations of gestational age categories (22-27, 28-32, 33-36, and at or above 37 weeks), small for gestational age (SGA), preeclampsia, and abruptio placenta in the first pregnancy with stillbirth and late abortion in the second were assessed by odds ratios (ORs) obtained by logistic regression. The baseline rate of stillbirth during the study period was 1.0% of all births from 16 weeks of gestation. After births with gestational age 22-27, 28-32, and 33-36 weeks of gestation, stillbirth was six, three and two times more likely to occur than after a term birth (OR 5.7, 95% confidence interval [CI] 4.2-7...Continue Reading


Aug 1, 1992·British Journal of Obstetrics and Gynaecology·J Dommisse, A J Tiltman
Oct 1, 1991·American Journal of Obstetrics and Gynecology·C M SalafiaL Silberman
May 1, 1974·American Journal of Epidemiology·O S Miettinen
May 30, 1993·Statistics in Medicine·D G Altman
Mar 1, 1996·Acta Obstetricia Et Gynecologica Scandinavica·S RasmussenKnut Dalaker
Feb 1, 1997·European Journal of Epidemiology·M GisslerE Hemminki
Jun 6, 1998·BMJ : British Medical Journal·R T LieL M Irgens
Feb 13, 1999·Paediatric and Perinatal Epidemiology·S RasmussenKnut Dalaker
Jun 17, 2000·Acta Obstetricia Et Gynecologica Scandinavica·L M Irgens
Nov 21, 2000·American Journal of Obstetrics and Gynecology·M C WilliamsW N Spellacy
Nov 15, 2001·Journal of Epidemiology and Community Health·P MagnusRolv Skjaerven
Oct 11, 2002·Statistics in Medicine·Harvey GoldsteinJon Rasbash
Mar 5, 2003·Early Human Development·Svein RasmussenTrond Markestad
Feb 20, 2004·The New England Journal of Medicine·Pamela J SurkanS Cnattingius
Mar 25, 2006·Early Human Development·Svein RasmussenSusanne Albrechtsen
Apr 4, 2006·Obstetrics and Gynecology·Hamisu M SalihuJohn Smulian
Apr 4, 2006·Obstetrics and Gynecology·Rolv T LieRolv Skjaerven
Sep 21, 2006·JAMA : the Journal of the American Medical Association·Olga BassoRolv Skjaerven
Jan 25, 2008·Thrombosis and Haemostasis·Willem J KistJohanna I P de Vries
Feb 5, 2009·BJOG : an International Journal of Obstetrics and Gynaecology·S Rasmussen, L M Irgens


Feb 10, 2010·Clinical Obstetrics and Gynecology·Jonathan P Shepherd, Halina M Zyczynski
Jul 28, 2010·Clinical Obstetrics and Gynecology·Erika F Werner, Charles J Lockwood
Aug 31, 2013·BMC Pregnancy and Childbirth·Michael J MahandeRolv T Lie
Jan 15, 2014·Taiwanese Journal of Obstetrics & Gynecology·Li-Chun LiuHer-Young Su
Jan 15, 2014·Journal of Clinical Epidemiology·David A CromwellIpek Gurol-Urganci
Jun 19, 2015·Acta Obstetricia Et Gynecologica Scandinavica·Siavash MaghsoudlouShahram Bahmanyar
Dec 20, 2011·American Journal of Obstetrics and Gynecology·Robert GoldenbergJ Villar
May 12, 2012·Revue D'épidémiologie Et De Santé Publique·A M NtambueF K Malonga
Sep 4, 2016·Taiwanese Journal of Obstetrics & Gynecology·Liangcheng WangAkiyoshi Takagi
Sep 1, 2017·BJOG : an International Journal of Obstetrics and Gynaecology·E MalacovaG Pereira
May 1, 2020·BMJ : British Medical Journal·Liv G KvalvikQuaker E Harmon

Related Concepts

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Separation Anxiety

Separation anxiety is a type of anxiety disorder that involves excessive distress and anxiety with separation. This may include separation from places or people to which they have a strong emotional connection with. It often affects children more than adults. Here is the latest research on separation anxiety.

KIF1A Associated Neurological Disorder

KIF1A associated neurological disorder (KAND) is a rare neurodegenerative condition caused by mutations in the KIF1A gene. KAND may present with a wide range and severity of symptoms including stiff or weak leg muscles, low muscle tone, a lack of muscle coordination and balance, and intellectual disability. Find the latest research on KAND here.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.