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Prioritization of SNPs for genome-wide association studies using an interaction model of genetic variation, gene expression, and trait variation

Molecules and Cells

Apr 1, 2012

Hyojung PaikDoheon Lee

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Abstract

The identification of true causal loci to unravel the statistical evidence of genotype-phenotype correlations and the biological relevance of selected single-nucleotide polymorphisms (SNPs) is a challenging issue in genome-wide association studies (GWAS). Here, we introduced a novel met...read more

Mentioned in this Paper

Gene Expression
Deviation, Epistatic
Single Nucleotide Polymorphism
Genetic Polymorphism
Genome-Wide Association Study
Brain Edema
Phenotype Determination
Candidate Gene Identification
Genotype Determination
Variation (Genetics)
Paper Details
References
  • References43
  • Citations1
12345

Prioritization of SNPs for genome-wide association studies using an interaction model of genetic variation, gene expression, and trait variation

Molecules and Cells

Apr 1, 2012

Hyojung PaikDoheon Lee

PMID: 22460606

DOI: 10.1007/s10059-012-2264-7

Abstract

The identification of true causal loci to unravel the statistical evidence of genotype-phenotype correlations and the biological relevance of selected single-nucleotide polymorphisms (SNPs) is a challenging issue in genome-wide association studies (GWAS). Here, we introduced a novel met...read more

Mentioned in this Paper

Gene Expression
Deviation, Epistatic
Single Nucleotide Polymorphism
Genetic Polymorphism
Genome-Wide Association Study

Related Papers

Paper Details
References
  • References43
  • Citations1
12345

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