Priority for children in cadaveric kidney sharing: the strategy adopted in Sao Paulo, Brazil

Pediatric Transplantation
Paulo C Koch NogueiraJose O M Pestana

Abstract

Early kidney transplantation is crucial in order to accomplish both optimal mental development and the best adult height in children with end-stage renal disease. The aim was to evaluate the efficacy of the child priority policy for cadaveric kidney sharing adopted in the State of Sao Paulo (Brazil). We performed a retrospective study of data collected by the Government Transplant Department in São Paulo, involving all patients included in the waiting list from August 13, 1998 to December 31, 2001. During the study period, the child priority policy had been changed giving: period A--from the outset up to March 14, 2001, where the rule was to direct cadaveric kidneys obtained from children <12 yr, to recipients <12 yr; period B--from March 14, 2001 onwards, where the policy had been broadened to include cadaveric donors <18 yr, destined for recipients <18 yr. We performed the analysis of the data comprising 8940 patients, 8622 being adults (mean age = 48.6 +/- 14.1 yr, 3594 females) and 318 children (mean age = 11.9 +/- 5.1 yr, 156 females). Over the 3.5-yr follow-up there were 1964 deaths [1933 adults and 31 children, odds ratio (OR) 0.37; 95% CI 0.25-0.55], 1032 living donor kidney transplants (963 adults and 69 children, OR 2...Continue Reading

References

May 1, 1983·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·H W SchnaperA M Robson
Aug 1, 1997·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M N TurenneP J Held
Jan 17, 2002·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·R N FineUNKNOWN North American Pediatric Renal Trasplant Cooperative Study (NAPRTCS)
Jan 17, 2002·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·C LoiratJ L Golmard
Oct 23, 2002·Archives of Disease in Childhood·J W GroothoffH S A Heymans
Jan 22, 2003·Child: Care, Health and Development·S J MaddenR S Trompeter
Aug 15, 2003·The New England Journal of Medicine·Ellen SheehyLawrence Hunsicker
Aug 15, 2003·The New England Journal of Medicine·Anthony J Langone, J Harold Helderman
Aug 30, 2003·BMJ : British Medical Journal·R J A SimsT Masud
Nov 25, 2003·The New England Journal of Medicine·Miguel A Frutos, Manuel Alonso

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Citations

Oct 15, 2013·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Luciana de Santis FeltranAlvaro Pacheco-Silva
Sep 25, 2007·Transplantation Proceedings·M GiessingS A Loening
Apr 16, 2013·Nephrology·Scott CampbellSteven McTaggart

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