Private lines of cortical visual information to the nucleus of the optic tract and dorsolateral pontine nucleus

Progress in Brain Research
C Distler, Klaus-Peter Hoffmann

Abstract

The subcortical nucleus of the optic tract and dorsal terminal nucleus of the accessory optic system (NOT-DTN), along with the dorsolateral pontine nucleus (DLPN), has been shown to play a pivotal role in controlling slow eye movements. Both nuclei are known to receive cortical input from striate and extrastriate cortex. To determine to what degree this cortical input arises from the same areas, and potentially from the same individual neurons, in one set of experiments we placed different retrograde tracers into the NOT-DTN and the DLPN. In the ipsilateral cortical hemisphere the two projections mainly overlapped in the middle temporal (MT) area, the middle superior temporal (MST) area, and the visual area in the fundus of the STS (FST) and the surrounding cortex. In these areas, neurons projecting to the NOT-DTN or the DLPN were closely intermingled. Nevertheless, only 3-11% of the labelled neurons in MT and MST were double-labelled in our various cases. In a second set of experiments, we identified neurons in areas MT and MST projecting to the DLPN and/or to the NOT-DTN by antidromic electrical stimulation. Again, neurons projecting to either target were located in close proximity to each other and in all subregions of MT an...Continue Reading

Citations

Dec 30, 2010·Psychological Science·Miriam SperingMarisa Carrasco
Jun 1, 2012·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Miriam Spering, Marisa Carrasco

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