Pro-epileptic changes in synaptic function can be accompanied by pro-epileptic changes in neuronal excitability

Trends in Neurosciences
H V WhealR C Cannon

Abstract

Repetitive sensory input, stroboscopic lights or repeated sounds can induce epileptic seizures in susceptible individuals. In order to understand the process we have to consider multiple factors. The output of a set of neurones is determined by the amount of excitatory synaptic input, the degree of positive feedback and their inherent electrical excitability, which can be modified by synaptic inhibition. Recent research has shown that it is possible to separate these phenomena, and that they do not always behave in unison.

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Citations

Sep 10, 2013·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Tímea BalassaGyörgy Bárdos
Jul 10, 2004·Journal of Physiology, Paris·Dominique DebanneMichaël Russier
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Jul 27, 2004·Science·Christophe BernardDaniel Johnston

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