Probabilistic source separation for robust fetal electrocardiography

Computational and Mathematical Methods in Medicine
R Vullings, M Mischi

Abstract

Blind source separation (BSS) techniques are widely used to extract signals of interest from a mixture with other signals, such as extracting fetal electrocardiogram (ECG) signals from noninvasive recordings on the maternal abdomen. These BSS techniques, however, typically lack possibilities to incorporate any prior knowledge on the mixing of the source signals. Particularly for fetal ECG signals, knowledge on the mixing is available based on the origin and propagation properties of these signals. In this paper, a novel source separation method is developed that combines the strengths and accuracy of BSS techniques with the robustness of an underlying physiological model of the fetal ECG. The method is developed within a probabilistic framework and yields an iterative convergence of the separation matrix towards a maximum a posteriori estimation, where in each iteration the latest estimate of the separation matrix is corrected towards a tradeoff between the BSS technique and the physiological model. The method is evaluated by comparing its performance with that of FastICA on both simulated and real multichannel fetal ECG recordings, demonstrating that the developed method outperforms FastICA in extracting the fetal ECG source s...Continue Reading

References

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Dec 16, 2010·IEEE Transactions on Bio-medical Engineering·Rik VullingsJan W M Bergmans
Jun 28, 2012·Physiological Measurement·Michael J RooijakkersMassimo Mischi

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Citations

Jun 5, 2015·Physics in Medicine and Biology·Orang AlemSvenja Knappe

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Methods Mentioned

BETA
ISS

Software Mentioned

ISS
MATLAB
FastICA

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