Get paper from

journal cover

Probabilities of Fitness Consequences for Point Mutations Across the Human Genome

bioRxiv

Jul 2, 2014

Brad GulkoAdam C Siepel

Get paper from

Abstract

We describe a novel computational method for estimating the probability that a point mutation at each position in a genome will influence fitness. These fitness consequence (fitCons) scores serve as evolution-based measures of potential genomic function. Our approach is to cluster genom...read more

Mentioned in this Paper

Gene Polymorphism
Human Cell Line
Study
Positioning Attribute
Genetic Polymorphism
Pan troglodytes
Genome
Point Mutation
Pan Genus
Gene Function
31
31
Paper Details
References
    • References
    • Citations

      References currently unavailable

      We're still populating references for this paper, please check back later.
    • References
    • Citations

      No citations available

      This paper may not have been cited yet.
  • Probabilities of Fitness Consequences for Point Mutations Across the Human Genome

    bioRxiv

    Jul 2, 2014

    Brad GulkoAdam C Siepel

    PMID: 990006825

    DOI: 10.1101/006825

    Abstract

    We describe a novel computational method for estimating the probability that a point mutation at each position in a genome will influence fitness. These fitness consequence (fitCons) scores serve as evolution-based measures of potential genomic function. Our approach is to cluster genom...read more

    Mentioned in this Paper

    Gene Polymorphism
    Human Cell Line
    Study
    Positioning Attribute
    Genetic Polymorphism
    31
    31

    Related Papers

    Paper Details
    References
    • References
    • Citations

      References currently unavailable

      We're still populating references for this paper, please check back later.
    • References
    • Citations

      No citations available

      This paper may not have been cited yet.
  • Get paper from

    © 2019 Meta ULC. All rights reserved.
    /papers/probabilities-of-fitness-consequences-for-point/990006825