PMID: 3753761Jan 10, 1986Paper

Probability of coding of a DNA sequence: an algorithm to predict translated reading frames from their thermodynamic characteristics

Nucleic Acids Research
A Tramontano, M Macchiato

Abstract

An algorithm to determine the probability that a reading frame codifies for a protein is presented. It is based on the results of our previous studies on the thermodynamic characteristics of a translated reading frame. We also develop a prediction procedure to distinguish between coding and non-coding reading frames. The procedure is based on the characteristics of the putative product of the DNA sequence and not on periodicity characteristics of the sequence, so the prediction is not biased by the presence of overlapping translated reading frames or by the presence of translated reading frames on the complementary DNA strand.

References

Jan 1, 1981·Annual Review of Microbiology·L GoldG Stormo
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Jun 1, 1981·Die Naturwissenschaften·M Eigen, R Winkler-Oswatitsch

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Citations

Jul 15, 1999·Computers & Chemistry·Y QuentinG Fichant
Dec 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·R L CharleboisW F Doolittle
Jan 1, 1995·Journal of Computational Biology : a Journal of Computational Molecular Cell Biology·M S Gelfand
Aug 25, 2005·Bioinformatics·Onkar C KulkarniBhaskar D Kulkarni
Oct 11, 1990·Nucleic Acids Research·M S Gelfand
Dec 25, 1992·Nucleic Acids Research·J W Fickett, C S Tung
May 5, 2012·Biochemical and Biophysical Research Communications·Baharak Goli, Achuthsankar S Nair
Jan 1, 1988·Computers in Biology and Medicine·A Tramontano, M F Macchiato
May 29, 1987·Biochemical and Biophysical Research Communications·J Kypr, J Mrázek
Aug 5, 1991·Journal of Molecular Biology·G A Fichant, C Burks

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