PMID: 6406301Jan 1, 1983Paper

Probability of the presence of glycosaminoglycans in aqueous humor

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
H Baba

Abstract

The crossed immunoelectrophoretic pattern of 62 eyes was reexamined, and 6 cases were selected for their abnormal patterns that demonstrated the presence of glycosaminoglycans in aqueous humor. Three of these cases were exfoliation syndrome, one was pigment liberation syndrome, and the other two were rhegmatogeneous retinal detachment. The abnormal electrophoretic patterns showed peculiar tailing and a biphasic pattern in albumin. Similar patterns could be reproduced in vitro by adding chondroitin sulfate to normal aqueous humor. Abnormal overproduction of glycosaminoglycans in exfoliation syndrome was indicated. Similar tailing of albumin was also noticed in 2 of 3 cases of rhegmatogeneous retinal detachment. It is supposed that the glycosaminoglycans produced by visual cells pass through the retinal break and vitreous cavity on the way to the anterior chamber. The Schwartz syndrome may be explained by this mechanism.

References

Nov 11, 1973·Experimental Eye Research·A Ringvold, G Husby
Feb 1, 1973·American Journal of Ophthalmology·A Schwartz
Jan 1, 1981·Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie. Albrecht Von Graefe's Archive for Clinical and Experimental Ophthalmology·J P HarnischP K Sinha
Jan 1, 1982·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·H Baba
Feb 1, 1965·Analytical Biochemistry·C B LAURELL

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Citations

Jan 1, 1983·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·H Baba
Nov 1, 1994·Survey of Ophthalmology·P A NetlandH I Covington
Mar 1, 1997·Survey of Ophthalmology·R S MoorthyN A Rao
Jun 6, 2012·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Ineke De Moortel, Valery M Nakariakov
Jun 6, 2012·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Clare E Parnell, Ineke De Moortel
Jul 9, 2009·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·William C HuttonJoseph J H Ackerman
Apr 1, 1996·Acta Ophthalmologica Scandinavica·G G KoliakosA C Trakatellis

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