Probable Hypocalcemia Induced Ventricular Fibrillation and Torsades de Pointes following Blood Product Administration

Curēus
Christian M Mosebach, Jeffrey Kluger

Abstract

A 35-year-old male underwent open-heart surgery and required multiple blood product transfusions. Citrate, a preservative in blood products, caused serum ionized calcium chelation leading to hypocalcemia, a prolonged corrected QT (QTc) interval, and separate episodes of ventricular fibrillation and torsades de pointes (TdP). This case highlights an uncommon complication of blood product transfusion-induced hypocalcemia with precipitant arrhythmia.

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