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Probing the compressibility of tumor cell nuclei by combined atomic force-confocal microscopy

Physical Biology

Dec 7, 2013

Marina KrauseKatarina Wolf

Abstract

The cell nucleus is the largest and stiffest organelle rendering it the limiting compartment during migration of invasive tumor cells through dense connective tissue. We here describe a combined atomic force microscopy (AFM)-confocal microscopy approach for measurement of bulk nuclear s...read more

Mentioned in this Paper

Tumor Cells, Uncertain Whether Benign or Malignant
Exploration With a Probe
Hydroxamic Acids
Hepatitis A
Muscular Stiffness
Histone deacetylase inhibitor
Cell Nucleus
Microscopy, Atomic Force
Microscopy, Confocal
Anatomical Compartments
Paper Details
References
  • References56
  • Citations27
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  • References56
  • Citations27
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Probing the compressibility of tumor cell nuclei by combined atomic force-confocal microscopy

Physical Biology

Dec 7, 2013

Marina KrauseKatarina Wolf

PMID: 24304807

DOI: 10.1088/1478-3975/10/6/065002

Abstract

The cell nucleus is the largest and stiffest organelle rendering it the limiting compartment during migration of invasive tumor cells through dense connective tissue. We here describe a combined atomic force microscopy (AFM)-confocal microscopy approach for measurement of bulk nuclear s...read more

Mentioned in this Paper

Tumor Cells, Uncertain Whether Benign or Malignant
Exploration With a Probe
Hydroxamic Acids
Hepatitis A
Muscular Stiffness
Histone deacetylase inhibitor
Cell Nucleus
Microscopy, Atomic Force
Microscopy, Confocal
Anatomical Compartments

Related Papers

Paper Details
References
  • References56
  • Citations27
12345...
  • References56
  • Citations27
123
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