Probiotics for induction of remission in ulcerative colitis.

The Cochrane Database of Systematic Reviews
Lakhbir KaurAnthony Kwaku Akobeng

Abstract

Ulcerative colitis is an inflammatory condition affecting the colon, with an annual incidence of approximately 10 to 20 per 100,000 people. The majority of people with ulcerative colitis can be put into remission, leaving a group who do not respond to first- or second-line therapies. There is a significant proportion of people who experience adverse effects with current therapies. Consequently, new alternatives for the treatment of ulcerative colitis are constantly being sought. Probiotics are live microbial feed supplements that may beneficially affect the host by improving intestinal microbial balance, enhancing gut barrier function and improving local immune response. To assess the efficacy of probiotics compared with placebo or standard medical treatment (5-aminosalicylates, sulphasalazine or corticosteroids) for the induction of remission in people with active ulcerative colitis. We searched CENTRAL, MEDLINE, Embase, and two other databases on 31 October 2019. We contacted authors of relevant studies and manufacturers of probiotics regarding ongoing or unpublished trials that may be relevant to the review, and we searched ClinicalTrials.gov. We also searched references of trials for any additional trials. Randomised contro...Continue Reading

References

Oct 6, 1997·BMJ : British Medical Journal·M EggerC Minder
Apr 3, 1999·JAMA : the Journal of the American Medical Association·R M PitkinL F Burmeister
Apr 30, 1999·Gastroenterology·K L MadsenR N Fedorak
Feb 24, 2001·Scandinavian Journal of Gastroenterology·R J KennedyK R Gardiner
Nov 28, 2002·Inflammatory Bowel Diseases·Oren ShiboletDaniel Rachmilewitz
Feb 6, 2003·Journal of the American College of Nutrition·Hideki IshikawaToru Otani
Oct 29, 1955·British Medical Journal·S C TRUELOVE, L J WITTS
May 11, 2004·World Journal of Gastroenterology : WJG·Hai-Hong CuiXue-Qing Chen
May 16, 2006·Alimentary Pharmacology & Therapeutics·M A ZoccoA Gasbarrini
Jan 29, 2009·The American Journal of Gastroenterology·Erasmo MieleAnnamaria Staiano
Jul 28, 2009·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Ajit SoodRakesh K Tandon
Jan 13, 2010·Alimentary Pharmacology & Therapeutics·R D CohenJ Chao
Oct 16, 2010·Journal of Epidemiology and Community Health·Holger SchünemannFaruque Ahmed
Oct 11, 2013·Inflammatory Bowel Diseases·Aleksander KragFlemming Bendtsen
Mar 7, 2014·Pathophysiology : the Official Journal of the International Society for Pathophysiology·Pinaki Panigrahi
Sep 30, 2015·Digestive Endoscopy : Official Journal of the Japan Gastroenterological Endoscopy Society·Hiroyuki TamakiMitsushige Shibatouge
Jul 2, 2016·Therapeutic Advances in Gastroenterology·Gionata FiorinoSilvio Danese
Dec 5, 2016·Lancet·Ryan UngaroJean-Frédéric Colombel
Jun 1, 2018·Journal of Pediatric Gastroenterology and Nutrition·Dan TurnerRichard K Russell
Aug 21, 2018·Journal of Transcultural Nursing : Official Journal of the Transcultural Nursing Society·Morgan E Braxton, Kim L Larson
Dec 24, 2018·Endocrine, Metabolic & Immune Disorders Drug Targets·Andrea BalliniFrancesco Inchingolo
Mar 14, 2019·The Cochrane Database of Systematic Reviews·Teck Guan OngAnthony K Akobeng
Aug 17, 2019·The Turkish Journal of Gastroenterology : the Official Journal of Turkish Society of Gastroenterology·Hua FanRui Gao

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Citations

Jul 18, 2020·The Cochrane Database of Systematic Reviews·Berkeley N LimketkaiAkinlolu Adedayo Adepoju
Mar 2, 2021·Frontiers in Cellular and Infection Microbiology·Ashton HarperRichard Day
Mar 16, 2021·Frontiers in Immunology·Fernanda CristoforiRuggiero Francavilla
Jul 3, 2021·Nutrients·Teresa Di ChioOsvaldo Borrelli
Jul 6, 2021·Journal of Diabetes and Metabolic Disorders·Amir Reza MoravejolahkamiMarjan Mansourian

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