Probiotics for the treatment of inflammatory bowel disease.

Current Gastroenterology Reports
Ganesh R VeerappanPatrick E Young

Abstract

Probiotics are organisms which provide a desired and beneficial effect on human health. With recent evidence implicating a disruption in the balance of the gastrointestinal microbiome and intestinal immunity as a potential trigger for inflammatory bowel disease (IBD), there has been growing interest in using probiotics as an adjunct to standard anti-inflammatory and immune suppressing therapy. Animal models describe potential and plausible mechanisms of action for probiotics to counter inflammation of colonic mucosa. Although there are insufficient data to recommend probiotics in ulcerative colitis or Crohn's disease, good evidence supports the use of specific probiotics for maintenance of remission in pouchitis. Although there are limited regulatory standards for the agents, probiotics are relatively safe with minimal reported side effects or contraindications. More rigorous studies need to be published supporting efficacy and safety of these agents before they become a mainstay of IBD medical treatment.

References

May 1, 1994·Gut·J G Ruseler-van EmbdenL M van Lieshout
Aug 29, 2000·Digestive Diseases and Sciences·M GuslandiP A Testoni
Oct 25, 2000·Journal of Pediatric Gastroenterology and Nutrition·P GuptaS Guandalini
Jan 10, 2002·Gastroenterology·Alexander SwidsinskiHerbert Lochs
Aug 9, 2002·The New England Journal of Medicine·Daniel K Podolsky
Dec 11, 2002·Best Practice & Research. Clinical Gastroenterology·Fergus Shanahan
Feb 14, 2003·Lancet·Francisco Guarner, Juan-R Malagelada
Mar 8, 2003·Alimentary Pharmacology & Therapeutics·J KuismaM Farkkila
Jul 4, 2003·European Journal of Gastroenterology & Hepatology·Mario GuslandiPier Alberto Testoni
Apr 27, 2004·Diseases of the Colon and Rectum·Martijn P GosselinkJohanneke G H Ruseler-van Embden
Apr 29, 2004·BMC Gastroenterology·Michael SchultzHeiko C Rath
Jun 30, 2005·The American Journal of Gastroenterology·Rodrigo BibiloniR Balfour Sartor
Aug 9, 2005·Gastroenterology Clinics of North America·Kevin P RiouxRichard N Fedorak
Oct 4, 2005·Alimentary Pharmacology & Therapeutics·B ShenB A Lashner
Dec 21, 2005·Annals of Internal Medicine·Giorgos BamiasUNKNOWN American Physiological Society
Mar 4, 2006·Gastroentérologie Clinique Et Biologique·Michaël BensoussanGuillaume Cadiot
May 16, 2006·Alimentary Pharmacology & Therapeutics·M A ZoccoA Gasbarrini
Jun 10, 2006·The American Journal of Clinical Nutrition·Robert J BoyleMimi L K Tang
Jul 5, 2006·Nature Clinical Practice. Gastroenterology & Hepatology·R Balfour Sartor
Oct 13, 2006·Journal of Pediatric Gastroenterology and Nutrition·Sonia MichailRobert Issenman
Oct 21, 2006·The Cochrane Database of Systematic Reviews·V E RolfeF Bath-Hextall
Jan 11, 2007·Digestive Diseases and Sciences·Irit ChermeshRami Eliakim

❮ Previous
Next ❯

Citations

Feb 7, 2013·Best Practice & Research. Clinical Gastroenterology·Charles RandallGregory Constantine
Aug 22, 2013·Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research·Jennifer L Owen, Mansour Mohamadzadeh
May 22, 2013·Clinical & Developmental Immunology·Rosario PelusoRaffaele Scarpa
May 7, 2014·Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquée, Nutrition Et Métabolisme·Amel Taibi, Elena M Comelli
Jun 28, 2014·The Proceedings of the Nutrition Society·Kristin A VerbekeEef Boets
Apr 1, 2014·FEBS Letters·Calum J WalshPaul D Cotter
Jan 7, 2015·Pharmacology & Therapeutics·Giovanni CammarotaDiego Currò
Dec 24, 2015·Frontiers in Immunology·Stefania De SantisMarcello Chieppa
Sep 12, 2015·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·C L KvasnovskyS Papagrigoriadis
Nov 10, 2015·BioMed Research International·Takahiko ShiinaYasutake Shimizu
Nov 26, 2015·Journal of Food Science and Technology·Kavita R PandeyBabu V Vakil
Aug 31, 2013·BioMed Research International·Franco ScaldaferriAntonio Gasbarrini
Mar 12, 2015·Journal of Immunology Research·Marcelo José Barbosa SilvaLiliane Martins dos Santos
Jan 20, 2017·The British Journal of Nutrition·Peter A BronJerry M Wells
Feb 12, 2014·The American Journal of Tropical Medicine and Hygiene·Richard A OberhelmanEamonn Connolly
May 27, 2014·Inflammatory Bowel Diseases·Konstantinos GerasimidisChristine A Edwards
Jun 12, 2014·Inflammatory Bowel Diseases·Houssam E Mardini, Alla Y Grigorian
Jul 15, 2015·Applied and Environmental Microbiology·Bokyung LeeMaria L Marco
Apr 22, 2015·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Mahdi ShadnoushMaryam Vaezjalali
Oct 15, 2018·Journal of Cellular Physiology·Bahman YousefiNarges Darabi
Sep 11, 2014·World Journal of Gastroenterology : WJG·Rok Orel, Tina Kamhi Trop
Sep 19, 2014·World Journal of Gastroenterology : WJG·Jessica CarrièreHang Thi Thu Nguyen
Feb 7, 2013·Current Opinion in Gastroenterology·Takayuki Yamamoto
Feb 24, 2016·World Journal of Gastroenterology : WJG·Franziska DurchscheinHeinz F Hammer
Aug 25, 2020·International Journal of Microbiology·Stellah ByakikaCharles Muyanja
Mar 8, 2020·The Journal of Nutritional Biochemistry·Ahmad Ud DinGuixue Wang
May 28, 2021·Environmental Science and Pollution Research International·Amr El-SayedMohamed Kamel
Sep 1, 2021·Periodontology 2000·Trang NguyenYvonne Kapila

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anti-inflammatory Treatments

A drug or substance that reduces inflammation (redness, swelling, and pain) in the body. Anti-inflammatory agents block certain substances in the body that cause inflammation and swelling. Discover the latest research on anti-inflammatory treatments here