Problem-based evidence: non-conventional methods of clinical investigations in surgery

Magyar sebészet
Akos Szucs, László Harsányi

Abstract

In the era of evidence-based medicine the application of randomised controlled trials (RCT) are crucial for innovations. In contrast with pharmacological studies surgical innovations have several difficulties: setting up a control group is not always simple, placebo is not easy to define and ethico-legal regulation of sham-operations is not well established yet. Risks of the learning curve, which are variable in time and space are quite characteristic for surgical innovations. There is a need therefore to develop new methodologies to overcome these difficulties and resulting in a widely acceptable outcome. The method of problem-based evidence (PBE) obtains the evidences from particular problems of health care using knowledge and experience; and hereby providing advantage for surgical innovations compared to RCT's. PBE provides more opportunity for organizing surgical research and their international acceptance.

References

Nov 4, 1992·JAMA : the Journal of the American Medical Association·UNKNOWN Evidence-Based Medicine Working Group
Oct 25, 2007·Medical Care·Susan D Horn, Julie Gassaway
Dec 1, 2009·Magyar sebészet·János Antal, László Harsányi

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