Abstract
Numerous investigations on procalcitonin (PCT) have been carried out, although few with large sample size. To deal with the complexity of sepsis, an understanding of PCT in heterogeneous clinical conditions is required. Hospitalized patients aged 10-79 years were included in this retrospective and cross-sectional study. PCT tests were assayed within 2 days of blood culture. A total of 2952 cases (from 2538 patients) were enrolled in this study, including 440 cases in the 'positive BC' group, 123 cases in the 'positive body fluid culture' group, and 2389 cases in the 'negative all culture' group. Median PCT values were 4.53 ng/ml, 2.95 ng/ml, and 0.49 ng/ml, respectively. Median PCT values in the gram-negative BC group and gram-positive BC group, respectively, were 6.99 ng/ml and 2.96 ng/ml. Median PCT values in the 'positive hydrothorax culture' group, 'positive ascites culture' group, 'positive bile culture' group, and 'positive cerebrospinal fluid culture' group, respectively, were 1.39 ng/ml, 8.32 ng/ml, 5.98 ng/ml, and 0.46 ng/ml. In all, 357 cases were classified into the 'sepsis' group, 150 of them were classified into the 'severe sepsis' group. Median PCT values were 5.63 ng/ml and 11.06 ng/ml, respectively. PCT could be...Continue Reading
References
Feb 27, 1993·Lancet·M AssicotC Bohuon
Jul 13, 2000·Critical Care Medicine·S SchwarzW Hacke
Nov 23, 2000·Intensive Care Medicine·K ReinhartM Meisner
Mar 31, 2001·Intensive Care Medicine·A EnguixM A Diéguez
Sep 8, 2001·Infection·M JerebF Strle
Oct 30, 2001·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·S LiaudatN Troillet
Jun 28, 2002·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Catherine ChirouzeBruno Hoen
Jun 29, 2002·Journal of Clinical Microbiology·S S RichterG V Doern
Jan 9, 2003·Journal of Clinical Microbiology·Erik L MunsonGary V Doern
Apr 12, 2003·Critical Care Medicine·Mitchell M LevyUNKNOWN SCCM/ESICM/ACCP/ATS/SIS
Aug 13, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Liliana SimonJacques Lacroix
Sep 29, 2004·The Lancet Infectious Diseases·A M C van RossumA M Oudesluys-Murphy
Dec 4, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Beat MüllerKenneth L Becker
Mar 12, 2005·Endocrinology·Philippe LinscheidBeat Müller
Jan 21, 2006·Critical Care Medicine·Jean-Louis VincentUNKNOWN Sepsis Occurrence in Acutely Ill Patients Investigators
Mar 1, 2006·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·R KhatibL B Johnson
Apr 21, 2006·Critical Care Medicine·Anand KumarMary Cheang
Sep 4, 2007·The European Respiratory Journal·M Christ-Crain, B Müller
Mar 28, 2009·Clinical Biochemistry·Fan-Su MengZhi-Feng Liu
Mar 20, 2010·Chest·Fabian MüllerUNKNOWN ProHOSP Study Group
Nov 17, 2010·Critical Care : the Official Journal of the Critical Care Forum·Sari KarlssonUNKNOWN Finnsepsis Study Group
Nov 19, 2010·Critical Care : the Official Journal of the Critical Care Forum·Cees van NieuwkoopJaap T van Dissel
Jun 20, 2012·The Journal of Infection·M TrompP Pickkers
Oct 2, 2012·Pediatric Emergency Care·Amanda J KasemHeidi Dalton
Oct 30, 2012·The Lancet Infectious Diseases·Mitchell M LevyR Phillip Dellinger
Jan 29, 2013·Critical Care Medicine·R Phillip DellingerUNKNOWN Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup
Feb 5, 2013·The Lancet Infectious Diseases·Christina WackerPeter Schlattmann
Feb 6, 2013·Clinical Chemistry and Laboratory Medicine : CCLM·Aldo Clerico, Mario Plebani
Feb 9, 2013·Clinical Chemistry and Laboratory Medicine : CCLM·Salvatore Di SommaGiuseppe Lippi
Jun 22, 2013·Critical Care : the Official Journal of the Critical Care Forum·Philipp SchuetzEric Gluck
Jan 8, 2014·Infection & chemotherapy·Seong-Ho Choi, Sang-Ho Choi
Feb 11, 2014·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Ge TianKun Qin
Feb 12, 2014·The American Journal of Emergency Medicine·Mohammad NaffaaWalid Saliba
Sep 23, 2014·Journal of Critical Care·José R A de AzevedoOsvaldo Malafaia
Dec 19, 2014·Scandinavian Journal of Infectious Diseases·Sofie Sommer HedegaardAnne-Mette Hvas
Citations
Mar 20, 2018·Infectious Diseases·Swati SharmaAnuj Sud
May 14, 2019·Clinical and Experimental Immunology·A MangognaR Bulla
Feb 27, 2018·Open Forum Infectious Diseases·Patrick Joseph, Eliot Godofsky
Jan 4, 2020·European Journal of Trauma and Emergency Surgery : Official Publication of the European Trauma Society·Dirouvarlen RamasawmyTimothy Craig Hardcastle
Jan 25, 2017·BMC Medicine·Ramon SagerPhilipp Schuetz
Oct 2, 2020·Journal of Endourology·Edward CapocciaDimitri Papagiannopoulos
Nov 28, 2018·Biosensors & Bioelectronics·Pei LiuPingping Shen
Aug 8, 2021·Journal of Clinical Laboratory Analysis·Qiqing GaoJie Peng