Procedure-related complications of open vs endoscopic fetal surgery for treatment of spina bifida in an era of intrauterine myelomeningocele repair: systematic review and meta-analysis

Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
E Araujo JúniorD Oepkes

Abstract

To assess and compare the rate of procedure-related complications after intrauterine treatment of spina bifida by endoscopic surgery and by open fetal surgery. Systematic literature searches in PubMed and SCOPUS databases were performed on 20 September 2015 to identify randomized controlled trials and observational studies on treatment of human spina bifida by endoscopic or open fetal surgery techniques. Only studies with ≥ 10 cases that were published in or after 2000 were included in the meta-analysis in order to reduce the risk of bias. Primary outcomes (complete dehiscence, focal dehiscence and/or markedly thin hysterotomy scar; preterm delivery < 34 weeks; mean gestational age at delivery) and secondary outcomes (oligohydramnios, prelabor rupture of membranes, placental abruption, chorioamnionitis and perinatal death) were assessed for both techniques. Precision of the estimated proportions was evaluated with 95% CIs. Inconsistency was assessed using the I(2) statistic. The search identified 1080 records that were examined based on title and abstract, of which 28 full-text articles were examined completely for eligibility. Nine records were excluded because cases were also described in other studies, leaving 19 records for...Continue Reading

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Citations

Feb 18, 2016·Archives of Gynecology and Obstetrics·Christian M DomröseArne Willruth
Mar 25, 2017·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Carlo V BellieniFelice Petraglia
May 13, 2017·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Sandra K KabagambeDiana L Farmer
Sep 21, 2018·The New Bioethics : a Multidisciplinary Journal of Biotechnology and the Body·Agustín SilberbergMagdalena Grillo
Dec 12, 2018·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Victoria Novoa Y NovoaRodrigo Ruano
Feb 22, 2018·Fetal Diagnosis and Therapy·Lucie GuilbaudJean-Marie Jouannic
Dec 14, 2017·Annual Review of Animal Biosciences·Sandra K KabagambeDiana L Farmer
Oct 2, 2019·Neurosurgical Focus·Pravesh S GadjradjTjeerd H R de Jong
Feb 1, 2020·Current Opinion in Obstetrics & Gynecology·Ling-Yien HiiSteven W Shaw
May 28, 2017·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Lucie GuilbaudJean-Marie Jouannic
Nov 10, 2020·Gynécologie, Obstétrique, Fertilité & Sénologie·S HautierJ Stirnemann
Mar 9, 2021·Taiwanese Journal of Obstetrics & Gynecology·Yu-Sin HuangTung-Yao Chang
May 22, 2021·Gynécologie, Obstétrique, Fertilité & Sénologie·P MacéJ Stirnemann

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