Proceedings of the 3rd BEAT-PCD Conference and 4th PCD Training School

BMC Proceedings
Hannah FarleyJune K Marthin

Abstract

Primary ciliary dyskinesia (PCD) is a chronic suppurative airways disease that is usually recessively inherited and has marked clinical phenotypic heterogeneity. Classic symptoms include neonatal respiratory distress, chronic rhinitis since early childhood, chronic otitis media, recurrent airway infections leading to bronchiectasis, chronic sinusitis, laterality defects with and without congenital heart disease including abnormal situs in approximately 50% of the cases, and male infertility. Lung function deteriorates progressively from childhood throughout life. 'Better Experimental Approaches to Treat Primary Ciliary Dyskinesia' (BEAT-PCD) is a network of scientists and clinicians coordinating research from basic science through to clinical care with the intention of developing treatments and diagnostics that lead to improved long-term outcomes for patients. BEAT-PCD activities are supported by EU funded COST Action (BM1407). The third BEAT-PCD conference and fourth PCD training school were held jointly in February 2018 in Lisbon, Portugal. Presentations and workshops focussed on advancing the knowledge and skills relating to PCD in: basic science, epidemiology, diagnostic testing, clinical management and clinical trials. The...Continue Reading

References

Dec 6, 2003·American Journal of Respiratory and Critical Care Medicine·Peadar G NooneMichael R Knowles
Oct 24, 2007·Nature Reviews. Molecular Cell Biology·Manfred FliegaufHeymut Omran
Feb 20, 2010·American Journal of Respiratory and Critical Care Medicine·June K MarthinKim G Nielsen
Jun 10, 2010·The European Respiratory Journal·C E KuehniUNKNOWN ERS Task Force on Primary Ciliary Dyskinesia in Children
Nov 26, 2011·Molecular Biology and Evolution·David HoogewijsThomas Hankeln
Dec 25, 2012·American Journal of Human Genetics·Alexandros OnoufriadisHannah M Mitchison
Sep 13, 2013·Annals of the American Thoracic Society·Margaret W LeighMichael R Knowles
Dec 10, 2013·Nature·Michelle G RoyChristopher M Evans
Feb 27, 2014·American Journal of Respiratory and Critical Care Medicine·Michael R KnowlesMaimoona A Zariwala
Mar 1, 2014·Chest·Adam J ShapiroUNKNOWN Genetic Disorders of Mucociliary Clearance Consortium
Nov 26, 2014·Pediatrics·Tara MullowneySharon Dell
Feb 18, 2015·Nature Communications·Christopher M EvansBurton F Dickey
Feb 27, 2015·Science Translational Medicine·Shaopeng YuanJohn V Fahy
May 16, 2015·The European Respiratory Journal·Jane S LucasAlexandra L Quittner
Jun 13, 2015·Archives of Disease in Childhood. Education and Practice Edition·Arvind NagraAnthony P Salmon
Sep 30, 2015·Pediatric Pulmonology·Adam J ShapiroUNKNOWN Genetic Disorders of Mucociliary Clearance Consortium
Feb 27, 2016·The European Respiratory Journal·Laura BehanJane S Lucas
Jun 17, 2016·Scientific Reports·Young Hoon SungHan-Woong Lee
Aug 6, 2016·The European Respiratory Journal·Myrofora GoutakiClaudia E Kuehni
Nov 12, 2016·The European Respiratory Journal·Jane S LucasClaudia E Kuehni
Jan 6, 2017·The European Respiratory Journal·Myrofora GoutakiUNKNOWN Genetic Disorders of Mucociliary Clearance Consortium
Jul 27, 2017·Expert Review of Respiratory Medicine·Jane S LucasWoolf T Walker
Sep 8, 2017·European Respiratory Review : an Official Journal of the European Respiratory Society·Bruna Rubbo, Jane S Lucas
Sep 13, 2017·Breathe·Claudia E Kuehni, Jane S Lucas
Nov 11, 2017·The European Respiratory Journal·Gert Jan VanakenSophie Christin-Maitre
Dec 23, 2017·The European Respiratory Journal·Myrofora GoutakiUNKNOWN French Reference Centre for Rare Lung Diseases
Apr 10, 2018·BMC Proceedings·Florian HalbeisenJane S Lucas

❮ Previous
Next ❯

Citations

Feb 15, 2020·ERJ Open Research·Myrofora GoutakiClaudia E Kuehni
Jun 5, 2020·ERJ Open Research·Cristina Ardura-GarciaClaudia E Kuehni
Jun 25, 2020·BMC Proceedings·Laura E GardnerClaire Hogg
Feb 6, 2021·The European Respiratory Journal·Myrofora GoutakiUNKNOWN BEAT-PCD Clinical Research Collaboration

❮ Previous
Next ❯

Methods Mentioned

BETA
transmission electron microscopy
imaging techniques
super-resolution microscopy
biopsies
electron microscopy
electron tomography
biopsy
light microscopy
lavage
exome sequencing

Software Mentioned

STORM
BEAT
HSVA
QOL
PCD
BESTCILIA
PICADAR
Basecamp

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.