Proceedings of the 4th Georg Rajka International Symposium on Atopic Dermatitis, Arcachon, France, September 15-17, 2005

The Journal of Allergy and Clinical Immunology
Alain TaïebArnold P Oranje

Abstract

The 4th Georg Rajka International Symposium on Atopic Dermatitis presented a comprehensive view of our current understanding and management of atopic dermatitis (AD). These proceedings highlight contributions related to the history of AD doctrines; genetic and epigenetic background; epidemiology; maturation of the immune system; infection and innate-adaptive immunity; epidermal inflammation, including neurogenic inflammation and pruritus; animal models; skin barrier; evidence-based therapy and education programs; prognostic and severity markers; and allergy testing. Several studies in animal models and human subjects point to impaired skin barrier function as a primary defect that facilitates the effect of environmental factors and immune dysregulation found in AD. The new frontier in AD therapy should, in the near future, reflect our better understanding of the skin barrier. The influence of environmental factors on the skin and other epithelial barriers in the perinatal period needs to be better understood to implement appropriate prevention programs.

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Citations

Jul 11, 2006·Current Allergy and Asthma Reports·Jonathan M Spergel, Donald Y M Leung
Jul 1, 2008·Current Allergy and Asthma Reports·Christian AndresJohannes Ring
Jul 16, 2014·The Journal of Allergy and Clinical Immunology. in Practice·Tali CzarnowickiEmma Guttman-Yassky
Feb 12, 2009·The Journal of Investigative Dermatology·Sara J Brown, W H Irwin McLean
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Apr 7, 2007·The Journal of Allergy and Clinical Immunology·Scott H Sicherer, Donald Y M Leung
Jan 17, 2007·Journal of the American Academy of Dermatology·Gérard TillesAlain Taïeb
Jun 2, 2014·The Journal of Allergy and Clinical Immunology·Christian ColeSara J Brown
Jun 6, 2009·Physiological Genomics·Pierre CamaterosDanuta Radzioch
Aug 22, 2014·Journal of Rehabilitation Research and Development·Paula J MyersJames A Henry

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Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.