Process control analysis of IMRT QA: implications for clinical trials

Physics in Medicine and Biology
Todd PawlickiClaribel Bonilla

Abstract

The purpose of this study is two-fold: first is to investigate the process of IMRT QA using control charts and second is to compare control chart limits to limits calculated using the standard deviation (sigma). Head and neck and prostate IMRT QA cases from seven institutions in both academic and community settings are considered. The percent difference between the point dose measurement in phantom and the corresponding result from the treatment planning system (TPS) is used for analysis. The average of the percent difference calculations defines the accuracy of the process and is called the process target. This represents the degree to which the process meets the clinical goal of 0% difference between the measurements and TPS. IMRT QA process ability defines the ability of the process to meet clinical specifications (e.g. 5% difference between the measurement and TPS). The process ability is defined in two ways: (1) the half-width of the control chart limits, and (2) the half-width of +/-3sigma limits. Process performance is characterized as being in one of four possible states that describes the stability of the process and its ability to meet clinical specifications. For the head and neck cases, the average process target ac...Continue Reading

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Citations

Apr 6, 2013·Medical Physics·Marco CarloneMiller Macpherson
Sep 18, 2013·Journal of Digital Imaging·Jayashree Kalpathy-CramerClifton D Fuller
Aug 5, 2014·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Erminia InfusinoLucio Trodella
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Apr 3, 2016·Medical Physics·Jennifer M Steers, Benedick A Fraass
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Jun 24, 2015·Journal of Applied Clinical Medical Physics·Francisco Clemente-Gutiérrez, Consuelo Pérez-Vara
Sep 18, 2013·Physics in Medicine and Biology·Taweap SanghangthumTodd Pawlicki
Jun 15, 2019·Journal of Applied Clinical Medical Physics·Sandra M MeyersDaniel Létourneau
Oct 27, 2021·Physical and Engineering Sciences in Medicine·Parminder BasranClive Baldock

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