Processing speed: a strong predictor of verbal memory performance in schizophrenia

Journal of Clinical and Experimental Neuropsychology
G BrébionLyn S Pilowsky

Abstract

The role of slowing of processing speed in verbal memory impairment in patients with schizophrenia was investigated. Forty-one patients with schizophrenia and 41 healthy control subjects were administered a verbal memory task involving free recall of three lists of words, which varied in their degree of semantic organization. Standard processing speed tests were administered as well. Regression analyses were conducted on the number of words recalled in each list. A global processing speed measure was a significant predictor of the recall of each list in patients. Patients were very significantly impaired in the recall of the three lists relative to healthy controls. However, when the processing speed measure was entered in the regression, the significance of diagnosis was considerably reduced for one of the lists, with no semantic organization, and eliminated for the other two lists which contained semantic organization. These findings suggest that slowing in processing speed is an important contributor to verbal memory impairment in patients with schizophrenia. The possible role of various specific slowing functions is discussed.

References

Jul 1, 1996·Psychological Review·T A Salthouse
Mar 1, 1997·Psychological Medicine·G BrébionJ M Gorman
Jul 11, 1998·Schizophrenia Research·G BrébionJ M Gorman
Apr 11, 2001·Schizophrenia Research·B J Jogems-KostermanW Hulstijn
Oct 25, 2002·Memory·Fergus I M Craik
Nov 5, 2002·Schizophrenia Research·Marilyn HartmanHeather McCann
Feb 7, 2003·Journal of the International Neuropsychological Society : JINS·William S KremenMing T Tsuang
May 23, 2003·Developmental Psychology·Susan A RoseJeffery J Jankowski
Nov 6, 2003·Neuropsychology·Esther A E HolthausenRobert J van den Bosch
Apr 22, 2004·Neuropsychology·Gildas BrébionLyn S Pilowsky
Oct 8, 2004·Schizophrenia Research·Marije van BeilenAnke Bouma

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Citations

Dec 17, 2008·Neurotoxicity Research·José Manuel Rodríguez-SánchezJosé Luis Vázquez-Barquero
Dec 15, 2006·Journal of the International Neuropsychological Society : JINS·Gildas BrébionLyn S Pilowsky
Jul 9, 2008·Journal of Clinical and Experimental Neuropsychology·Mareike AltgassenJacqueline Zollig
Jul 9, 2008·Journal of Clinical and Experimental Neuropsychology·Gildas BrébionLyn S Pilowsky
Sep 22, 2007·Schizophrenia Research·Robert M RothAndrew J Saykin
May 19, 2009·Journal of Attention Disorders·Jens Egeland, Iwona Kovalik-Gran
Apr 24, 2018·Journal of Neuropsychology·Margherita BechiRoberto Cavallaro
Mar 9, 2011·Journal of the International Neuropsychological Society : JINS·Gildas BrébionAnthony S David
Oct 22, 2018·Neuropsychology Review·Julia M SheffieldDeanna M Barch

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