Processing speed and executive functions predict real-world everyday living skills in adolescents with early-onset schizophrenia.

European Child & Adolescent Psychiatry
Olga PuigJ Castro-Fornieles

Abstract

Cognition and clinical variables are known to be among the most predictive factors of real-world social functioning and daily living skills in adult-onset schizophrenia. Fewer studies have focused on their impact in adolescents with early-onset schizophrenia (EOS). The aim of this study is to examine the relationships and the predictive value of cognition and clinical variables on real-world daily living skills in a sample of adolescents with EOS. Cognitive, clinical and real-world everyday living skills measures were administered to 45 clinically and pharmacologically stabilized adolescent outpatients with EOS and 45 healthy control subjects matched by age and sex. Multi-variant analyses to compare cognitive and real-world functioning profiles between patients and controls and regression analysis to identify predictors of real-world functioning scores in patients were used. Adolescents with EOS showed a generalized cognitive and real-world daily living skills dysfunction. Several cognitive and clinical variables significantly correlated with real-world daily living skills functioning but only the processing speed and executive functions emerged as independent predictors of everyday living skills scores, explaining 25.1% of the...Continue Reading

References

Feb 14, 1978·Journal of Neurology·K S Hamsher, A L Benton
May 1, 1991·Journal of the American Academy of Child and Adolescent Psychiatry·J S WerryL Chard
Jul 1, 1990·Schizophrenia Research·D AddingtonB Schissel
Jan 1, 1995·European Archives of Psychiatry and Clinical Neuroscience·M SchmidtB Lay
May 1, 1996·Schizophrenia Research·A L HoffJ G Csernansky
Apr 3, 1998·Journal of Clinical and Experimental Neuropsychology·P M Moore, G A Baker
Jul 24, 1998·Scandinavian Journal of Psychology·B R RundG Bryhn
May 5, 2000·European Child & Adolescent Psychiatry·T BanaschewskiH Remschmidt
Nov 22, 2000·Schizophrenia Bulletin·B LayM H Schmidt
Jun 21, 2001·Audiology : Official Organ of the International Society of Audiology·K A NeijenhuisP Van der Broek
Jun 27, 2002·Schizophrenia Research·Dwight Dickinson, Robert D Coursey
May 27, 2003·Schizophrenia Research·Apostolos VourdasSophia Frangou
Nov 6, 2003·Neuropsychology·Esther A E HolthausenRobert J van den Bosch
Feb 26, 2004·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Joan Rosenbaum AsarnowEmily P McGrath
Mar 11, 2004·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Tom N Tombaugh
May 26, 2004·Psychiatry Research·Torill UelandBjørn R Rund
Nov 9, 2004·Schizophrenia Research·Michael F GreenRobert K Heaton
Mar 31, 2005·Journal of Autism and Developmental Disorders·Annelies de BildtRuud Minderaa
Jul 19, 2005·Biological Psychiatry·Joseph P RhinewineSanjiv Kumra
Jul 22, 2005·Journal of the American Academy of Child and Adolescent Psychiatry·Trevor BallageerRaj Haricharan
Aug 27, 2005·Schizophrenia Bulletin·Christian FleischhakerHelmut Remschmidt
Oct 8, 2005·Neuropsychology Review·Mario FioravantiLinda Clare
Oct 13, 2005·European Child & Adolescent Psychiatry·Bernd Röpcke, Christian Eggers
Jan 21, 2006·Acta Psychiatrica Scandinavica·J van OsJ M Kane
Apr 19, 2006·Journal of Clinical and Experimental Neuropsychology·Gildas BrébionLyn S Pilowsky
Apr 22, 2006·Schizophrenia Research·Birgitte FagerlundRalf P Hemmingsen
Sep 12, 2006·Schizophrenia Research·Jonathan RabinowitzHeinz Häfner
Sep 14, 2006·Acta Psychiatrica Scandinavica·H MengD Bürgin
Mar 16, 2007·Acta Psychiatrica Scandinavica·J Addington, D Addington
Jun 22, 2007·Journal of the American Academy of Child and Adolescent Psychiatry·Kelly L CervellioneSanjiv Kumra
Aug 2, 2007·Journal of the American Academy of Child and Adolescent Psychiatry·Jean A FrazierLinmarie Sikich
Sep 27, 2007·European Child & Adolescent Psychiatry·Nora S VyasSophia Frangou
Oct 19, 2007·Acta Psychiatrica Scandinavica·T Burns, D Patrick
Nov 21, 2007·Schizophrenia Bulletin·Sophia FrangouApostolos Vourdas

❮ Previous
Next ❯

Citations

Nov 6, 2012·Journal of Psychiatric Research·B Kluwe-SchiavonR Grassi-Oliveira
Dec 10, 2015·European Psychiatry : the Journal of the Association of European Psychiatrists·E ChubarovG Zalsman
Jul 14, 2017·The International Journal of Social Psychiatry·Bernard J Gallagher, Brian J Jones
Mar 1, 2016·Human Ecology: an Interdisciplinary Journal·C P Peña-VenegasP C Struik
Jan 4, 2020·European Child & Adolescent Psychiatry·Jordina TorInmaculada Baeza
Sep 9, 2020·The Journal of Head Trauma Rehabilitation·Rachel Zachar-TiradoJacobus Donders

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.