Production of arachidonic acid and dihomo-gamma-linolenic acid from glycerol by oil-producing filamentous fungi, Mortierella in the ARS culture collection

Journal of Industrial Microbiology & Biotechnology
Ching T Hou

Abstract

The filamentous fungi of the genus Mortierella are known to produce arachidonic acid from glucose, and the species alpina is currently used in industrial production of arachidonic acid in Japan. In anticipation of a large excess of the co-product glycerol from the national biodiesel program, we are trying to find new uses for bioglycerin. We screened 12 Mortierella species: M. alpina NRRL 6302, M. claussenii NRRL 2760, M. elongata NRRL 5246, M. epigama NRRL 5512, M. humilis NRRL 6369, M. hygrophila NRRL 2591, M. minutissima NRRL 6462, M. multidivaricata NRRL 6456, M. nantahalensis NRRL 5216, M. parvispora NRRL 2941, M. sepedonioides NRRL 6425, and M. zychae NRRL 2592 for their production of arachidonic acid (AA) and dihomo-gamma-linolenic acid (DGLA) from glycerol. With glucose as substrate all of the strains tested produced AA and DGLA. The total fatty acid content of 125 mg/g cell dry weight (CDW) and fatty acid composition for AA (19.63%) and DGLA (5.95%) in the mycelia of M. alpina grown on glucose were comparable with those reported by Takeno et al. (Appl Environ Microbiol 71:5124-5128, 2005). With glycerol as substrate all species tested grew on glycerol and produced AA and DGLA except M. nantahalensis NRRL 5216, which co...Continue Reading

References

Jan 1, 1992·Progress in Lipid Research·D F Horrobin
Jan 1, 1986·Annual Review of Biochemistry·P NeedlemanJ B Lefkowith
Jul 1, 1992·Applied and Environmental Microbiology·S JareonkitmongkolH Yamada

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Citations

Feb 11, 2012·Applied Microbiology and Biotechnology·R W NicolW D Lubitz
May 2, 2013·Critical Reviews in Biotechnology·Xiao-Jun JiPing-Kai Ouyang
Mar 12, 2015·Analytical and Bioanalytical Chemistry·Ute MünchbergJürgen Popp
Sep 29, 2010·Prikladnaia biokhimiia i mikrobiologiia·E P FeofilovaA A Ivashechkin
Nov 12, 2014·Applied Microbiology and Biotechnology·Kai Heimel
Mar 1, 2011·Prikladnaia biokhimiia i mikrobiologiia·É G DediukhinaM B Vaĭnshteĭn
Sep 29, 2011·Critical Reviews in Biotechnology·Swati KhannaVijayanand S Moholkar
Jan 4, 2017·Applied Microbiology and Biotechnology·Igor G MorgunovMikhail B Vainshtein

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