Production of bacteriophage mutants by a disturbance of deoxyribonucleic acid metabolism

PMID: 13358788Sep 8, 1956Paper

Production of bacteriophage mutants by a disturbance of deoxyribonucleic acid metabolism

Nature

R M LITMAN, A B Pardee

Abstract

No abstract listed.

References

Preparation, purification, and properties of E. coli virus T2

May 1, 1952·The Journal of General Physiology·R M HERRIOTT, J L BARLOW

Incorporation of halogenated pyrimidines into the deoxyribonucleic acids of Bacterium coli and its bacteriophages

Aug 14, 1954·Nature·D B DUNNG GRIBOFF

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Citations

Sister chromatid differential staining and NOR activity of BrdU-resistant sublines

Aug 1, 1985·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·Y YongshanX Xiahui

Temporal sequence of mutation for 6-thioguanine resistance in synchronised Chinese hamster cells

Jul 1, 1976·TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·I RaskóL Dallmann

The effects of deuterium oxide on bacteria

Jan 1, 1961·Zeitschrift für Vererbungslehre·R DE GIOVANNI

Bromodeoxyuridine mutagenesis in mammalian cells is stimulated by purine deoxyribonucleosides

Sep 1, 1979·Somatic Cell Genetics·E R Kaufman, R L Davidson

Isolation of mutants of CHO cells resistant to 6(p-hydroxyphenylazo)-uracil I. A novel BrdU cross-resistant phenotype

Mar 1, 1983·Somatic Cell Genetics·E ArpaiaL Siminovitch

5-Bromouracil and induced production of fusaric acid by Fusarium oxysporum f. lycopersici in culture

Jun 15, 1967·Experientia·R K Kakkar

The induction of mutants of bacteriophage T2 by 5-bromouracil. IV. Kinetics of bromouracil-induced mutagenesis

Jul 29, 1960·Biochimica Et Biophysica Acta·R M LITMAN, A B PARDEE

Effect of 8-azaguanine on oxidative phosphorylation of mouse-liver mitochondria

Apr 23, 1962·Biochimica Et Biophysica Acta·P L BERGQUIST

Effects of ultraviolet radiation on mammalian cells. I. Induction of chromosome aberrations

Feb 1, 1965·Mutation Research·E H Chu

Effect of 5-bromodeoxyuridine on the male meiosis in Chinese hamsters (Cricetus griseus)

Jul 1, 1968·Mutation Research·A B Murkherjee

Mutagenic effect of BUdR in diploid human fibroblasts

Mar 1, 1974·Mutation Research·R M Stark, J W Littlefield

The efficiency and extent of mutagenic activity of some new mutagens of base-analogue type

Jan 1, 1978·Mutation Research·C Janion

Altered CTP synthetase activity confers resistance to 5-bromodeoxyuridine toxicity and mutagenesis

Jun 1, 1986·Mutation Research·E R Kaufman

The role of deoxyribonucleotide metabolism in 5-bromo-2'-deoxyuridine mutagenesis in mammalian cells

Jul 1, 1988·Mutation Research·E R Kaufman

Mutagenicity, toxicity and repair of DNA base damage induced by oxidation

Nov 26, 2003·Mutation Research·Svein Bjelland, Erling Seeberg

PaJaMas in Paris

Nov 5, 2002·Trends in Genetics : TIG·Arthur B Pardee

EQUILIBRIUM SEDIMENTATION OF MACROMOLECULES IN DENSITY GRADIENTS

Jul 15, 1957·Proceedings of the National Academy of Sciences of the United States of America·M MeselsonJ Vinograd

INDUCTION OF SPECIFIC MUTATIONS WITH 5-BROMOURACIL

Feb 1, 1958·Proceedings of the National Academy of Sciences of the United States of America·S Benzer, E Freese

MUTATIONAL HETEROZYGOTES IN BACTERIOPHAGES

Oct 1, 1959·Proceedings of the National Academy of Sciences of the United States of America·D Pratt, G S Stent

Effect of 5-bromodeoxyuridine on mamalian chromosomes

Mar 15, 1961·Proceedings of the National Academy of Sciences of the United States of America·T C HSU, C E SOMERS

ON THE TOPOGRAPHY OF THE GENETIC FINE STRUCTURE

Mar 1, 1961·Proceedings of the National Academy of Sciences of the United States of America·S Benzer

The chemical and mutagenic specificity of hydroxylamine

Jun 15, 1961·Proceedings of the National Academy of Sciences of the United States of America·E FREESEE B FREESE

Deoxyuridylate kinase activity and deoxyuridinetriphosphatase in Escherichia coli

Feb 1, 1962·Proceedings of the National Academy of Sciences of the United States of America·G R GREENBERG, R L SOMERVILLE

Reversal of mutant phenotypes by 5-fluorouracil: an approach to nucleotide sequences in messenger-RNA

Apr 15, 1962·Proceedings of the National Academy of Sciences of the United States of America·S P CHAMPE, S BENZER

The mechanism of 5-bromouracil mutagenesis in the bacteriophage T alpha

Sep 15, 1962·Proceedings of the National Academy of Sciences of the United States of America·B E TERZAGHIF W STAHL

Studies on mechanisms for the maintenance of constant mutability: mutability and the resistance to mutagens

Jan 1, 1966·Proceedings of the National Academy of Sciences of the United States of America·S ZamenhofP J Zamenhof

Bromodeoxyuridine dependence--a new mutation in mammalian cells

Jan 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·R L Davidson, M D Bick

Total substitution of bromodeoxyuridine for thymidine in the DNA of a bromodeoxyuridine-dependent cell line

May 1, 1974·Proceedings of the National Academy of Sciences of the United States of America·M D Bick, R L Davidson

Biological consequences of incorporation of 5-fluorocytidine in the RNA of 5-fluorouracil-treated eukaryotic cells

May 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·M K Gleason, H Fraenkel-Conrat

Bromodeoxyuridine mutagenesis in mammalian cells: mutagenesis is independent of the amount of bromouracil in DNA

Oct 1, 1978·Proceedings of the National Academy of Sciences of the United States of America·E R Kaufman, R L Davidson

Selection of mammalian cells resistant to a chloramphenicol analog.

May 1, 1975·The Journal of Cell Biology·R B Wallace, K B Freeman

Regulation of rat myosin light-chain synthesis in heterokaryons between 5-bromodeoxyuridine-blocked rat myoblasts and differentiated chick myocytes

Jun 1, 1983·The Journal of Cell Biology·W E Wright, J Aronoff

STUDIES ON ANTIBODY PRODUCTION : VII. THE EFFECT OF 5-BROMODEOXYURIDINE ON THE IN VITRO ANAMNESTIC ANTIBODY RESPONSE.

Jun 1, 1963·The Journal of Experimental Medicine·T F O'Brien, A H Coons

Thermal denaturation of DNA from bromodeoxyuridine substituted cells

Jan 1, 1976·Nucleic Acids Research·B R Cullen, M D Bick

Relationships, established and prospective, between viruses and cancer

Sep 30, 1958·Annals of the New York Academy of Sciences·W M STANLEY

Lethal and mutagenic effects of 5-iodouracil on bacteriophage T4td8rII.

Feb 1, 1977·Antimicrobial Agents and Chemotherapy·D M Byrd, W H Prusoff

Multiplicity reactivation of 5-iodouracil-substituted, nonviable bacteriophage T4td8.

Nov 1, 1975·Antimicrobial Agents and Chemotherapy·D M Byrd, W H Prusoff

Inhibition of calmodulin-dependent kinase kinase blocks human cytomegalovirus-induced glycolytic activation and severely attenuates production of viral progeny

Nov 19, 2010·Journal of Virology·Jessica McArdleJoshua Munger

Human cytomegalovirus induces the activity and expression of acetyl-coenzyme A carboxylase, a fatty acid biosynthetic enzyme whose inhibition attenuates viral replication.

Apr 8, 2011·Journal of Virology·Cody M SpencerJoshua Munger

HCMV targets the metabolic stress response through activation of AMPK whose activity is important for viral replication.

Feb 1, 2012·PLoS Pathogens·Jessica McArdleJoshua Munger

The effect of 5-iodouracil on the growth and biosynthetic processes of bacteriophage T4td8 in the absence of light

Feb 1, 1976·Chemico-biological Interactions·D M Byrd, W H Prusoff

Effect of 5-bromodeoxyuridine incorporation on survival of cultured mammalian cells

Nov 26, 1962·Biochimica Et Biophysica Acta·M T HAKALA

Mutagenicity of 5-halodeoxyuridines to diploid human lymphoblasts

Aug 15, 1976·Life Sciences·B W PenmanW G Thilly

Chemical modification of viral ribonucleic acid. I. Alkylating agents

Apr 29, 1961·Biochimica Et Biophysica Acta·H FRAENKEL-CONRAT

Antiviral iodinated pyrimidine deoxyribonucleosides: 5-iodo-2'-deoxyuridine; 5-iodo-2'-deoxycytidine; 5-iodo-5'-amino-2',5'-dideoxyuridine

Jan 1, 1979·Pharmacology & Therapeutics·W H PrusoffJ Walker

Chemical mutagenesis. II. Some observations on the new morphogenetic variations induced in Aspergillus oryzae Wehmer by 6-azauracil

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Phage therapy uses bacterial viruses (bacteriophages) to treat bacterial infections and is widely being recognized as an alternative to antibiotics. Here is the latest research.

Production of bacteriophage mutants by a disturbance of deoxyribonucleic acid metabolism

Abstract

References

Preparation, purification, and properties of E. coli virus T2

Incorporation of halogenated pyrimidines into the deoxyribonucleic acids of Bacterium coli and its bacteriophages

Citations

Sister chromatid differential staining and NOR activity of BrdU-resistant sublines

Temporal sequence of mutation for 6-thioguanine resistance in synchronised Chinese hamster cells

The effects of deuterium oxide on bacteria

Bromodeoxyuridine mutagenesis in mammalian cells is stimulated by purine deoxyribonucleosides

Isolation of mutants of CHO cells resistant to 6(p-hydroxyphenylazo)-uracil I. A novel BrdU cross-resistant phenotype

5-Bromouracil and induced production of fusaric acid by Fusarium oxysporum f. lycopersici in culture

The induction of mutants of bacteriophage T2 by 5-bromouracil. IV. Kinetics of bromouracil-induced mutagenesis

Effect of 8-azaguanine on oxidative phosphorylation of mouse-liver mitochondria

Effects of ultraviolet radiation on mammalian cells. I. Induction of chromosome aberrations

Effect of 5-bromodeoxyuridine on the male meiosis in Chinese hamsters (Cricetus griseus)

Mutagenic effect of BUdR in diploid human fibroblasts

The efficiency and extent of mutagenic activity of some new mutagens of base-analogue type

Altered CTP synthetase activity confers resistance to 5-bromodeoxyuridine toxicity and mutagenesis

The role of deoxyribonucleotide metabolism in 5-bromo-2'-deoxyuridine mutagenesis in mammalian cells

Mutagenicity, toxicity and repair of DNA base damage induced by oxidation

PaJaMas in Paris

EQUILIBRIUM SEDIMENTATION OF MACROMOLECULES IN DENSITY GRADIENTS

INDUCTION OF SPECIFIC MUTATIONS WITH 5-BROMOURACIL

MUTATIONAL HETEROZYGOTES IN BACTERIOPHAGES

Effect of 5-bromodeoxyuridine on mamalian chromosomes

ON THE TOPOGRAPHY OF THE GENETIC FINE STRUCTURE

The chemical and mutagenic specificity of hydroxylamine

Deoxyuridylate kinase activity and deoxyuridinetriphosphatase in Escherichia coli

Reversal of mutant phenotypes by 5-fluorouracil: an approach to nucleotide sequences in messenger-RNA

The mechanism of 5-bromouracil mutagenesis in the bacteriophage T alpha

Studies on mechanisms for the maintenance of constant mutability: mutability and the resistance to mutagens

Bromodeoxyuridine dependence--a new mutation in mammalian cells

Total substitution of bromodeoxyuridine for thymidine in the DNA of a bromodeoxyuridine-dependent cell line

Biological consequences of incorporation of 5-fluorocytidine in the RNA of 5-fluorouracil-treated eukaryotic cells

Bromodeoxyuridine mutagenesis in mammalian cells: mutagenesis is independent of the amount of bromouracil in DNA

Selection of mammalian cells resistant to a chloramphenicol analog.

Regulation of rat myosin light-chain synthesis in heterokaryons between 5-bromodeoxyuridine-blocked rat myoblasts and differentiated chick myocytes

STUDIES ON ANTIBODY PRODUCTION : VII. THE EFFECT OF 5-BROMODEOXYURIDINE ON THE IN VITRO ANAMNESTIC ANTIBODY RESPONSE.

Thermal denaturation of DNA from bromodeoxyuridine substituted cells

Relationships, established and prospective, between viruses and cancer

Lethal and mutagenic effects of 5-iodouracil on bacteriophage T4td8rII.

Multiplicity reactivation of 5-iodouracil-substituted, nonviable bacteriophage T4td8.

Inhibition of calmodulin-dependent kinase kinase blocks human cytomegalovirus-induced glycolytic activation and severely attenuates production of viral progeny

Human cytomegalovirus induces the activity and expression of acetyl-coenzyme A carboxylase, a fatty acid biosynthetic enzyme whose inhibition attenuates viral replication.

HCMV targets the metabolic stress response through activation of AMPK whose activity is important for viral replication.

The effect of 5-iodouracil on the growth and biosynthetic processes of bacteriophage T4td8 in the absence of light

Effect of 5-bromodeoxyuridine incorporation on survival of cultured mammalian cells

Mutagenicity of 5-halodeoxyuridines to diploid human lymphoblasts

Chemical modification of viral ribonucleic acid. I. Alkylating agents

Antiviral iodinated pyrimidine deoxyribonucleosides: 5-iodo-2'-deoxyuridine; 5-iodo-2'-deoxycytidine; 5-iodo-5'-amino-2',5'-dideoxyuridine

STUDIES ON THE INDUCTION OF MUTATIONS IN BACTERIOPHAGE T4 BY ULTRAVIOLET IRRADIATION AND BY PROFLAVIN

Antiviral action of 5-bromo-2'-deoxyuridine and polyoma virus-specific RNA synthesis

Error frequency in 5S RNA from cells grown in 5-bromodeoxyuridine

Studies on induced reversions at the arginine locus of Aspergillus chevalieri (Mangin)

Chemical mutagenesis. II. Some observations on the new morphogenetic variations induced in Aspergillus oryzae Wehmer by 6-azauracil

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