Production of Catalyst-Free Hyperpolarised Ethanol Aqueous Solution via Heterogeneous Hydrogenation with Parahydrogen

Scientific Reports
Oleg G SalnikovIgor V Koptyug

Abstract

An experimental approach for the production of catalyst-free hyperpolarised ethanol solution in water via heterogeneous hydrogenation of vinyl acetate with parahydrogen and the subsequent hydrolysis of ethyl acetate was demonstrated. For an efficient hydrogenation, liquid vinyl acetate was transferred to the gas phase by parahydrogen bubbling and almost completely converted to ethyl acetate with Rh/TiO2 catalyst. Subsequent dissolution of ethyl acetate gas in water containing OH(-) ions led to the formation of catalyst- and organic solvent-free hyperpolarised ethanol and sodium acetate. These results represent the first demonstration of catalyst- and organic solvent-free hyperpolarised ethanol production achieved by heterogeneous hydrogenation of vinyl acetate vapour with parahydrogen and the subsequent ethyl acetate hydrolysis.

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Citations

Nov 3, 2016·Chemistry : a European Journal·Kirill V KovtunovEduard Y Chekmenev
Jun 24, 2017·Angewandte Chemie·Kirill V KovtunovBoyd M Goodson
Nov 6, 2018·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Anand ManoharanSimon B Duckett
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Nov 30, 2019·Physical Chemistry Chemical Physics : PCCP·Ekaterina V PokochuevaIgor V Koptyug
Feb 3, 2021·Magma·Francesca ReineriSilvio Aime
Apr 8, 2021·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Eduard Y ChekmenevIgor V Koptyug
May 1, 2021·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Oleg G SalnikovEduard Y Chekmenev
May 11, 2021·Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry·Ekaterina V PokochuevaIgor V Koptyug
Feb 27, 2021·Angewandte Chemie·Andrey N PravdivtsevJan-Bernd Hövener
Aug 1, 2019·The Journal of Physical Chemistry. C, Nanomaterials and Interfaces·Oleg G SalnikovEduard Y Chekmenev

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Methods Mentioned

BETA
chemical modification
NMR

Software Mentioned

SABRE

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