Production of chemokines in respiratory syncytial virus infection with central nervous system manifestations

Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy
Hisashi KawashimaYuichi Kato

Abstract

Respiratory syncytial virus (RSV) infection in children can be associated with acute encephalopathy. However, the roles of cytokines in the cerebrospinal fluid (CSF) of such patients remain unevaluated. In this study, a profile of 17 cytokines was determined for eight RSV-infected children with neurological complications. In one patient with high levels of 13 cytokines, a cytokine storm was considered to have occurred. Interleukin (IL)-6, IL-8, monocyte chemoattractant protein (MCP)-1, and macrophage inflammatory protein (MIP)-1β levels were also high in other patients. These data suggest that chemokines in CSF play roles in neurological complications in RSV-infected children.

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Citations

Jan 7, 2016·The International Journal of Neuroscience·Shinichiro MorichiHisashi Kawashima
Oct 16, 2014·Reviews in Medical Virology·Karen BohmwaldAlexis M Kalergis
Jun 1, 2015·Current Opinion in Immunology·Karen BohmwaldAlexis M Kalergis
Jan 29, 2013·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Kenji MiyamotoOsamu Arisaka
Apr 20, 2017·Pediatrics International : Official Journal of the Japan Pediatric Society·Kazuhiro Uda, Katsuhiko Kitazawa
Oct 26, 2018·Korean journal of pediatrics·Teahyen ChaJin-Hwa Moon
Aug 19, 2020·Expert Opinion on Pharmacotherapy·Alexis M KalergisSusan M Bueno
Apr 19, 2020·Molecular Medicine·Jorge A SotoAlexis M Kalergis
Dec 8, 2019·Journal of Neurochemistry·Bertrand BrycheNicolas Meunier
Jul 2, 2019·Pediatrics International : Official Journal of the Japan Pediatric Society·Yukihiko KawasakiMitsuaki Hosoya
Nov 13, 2018·Frontiers in Cellular Neuroscience·Karen BohmwaldAlexis M Kalergis
Apr 2, 2021·Clinical Microbiology Reviews·Nicola ClementiNicasio Mancini
Oct 8, 2021·Continuum : Lifelong Learning in Neurology·Michael A Pizzi

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