PMID: 9676044Feb 1, 1996Paper

Production of extracellular protease by Streptomyces fradiae

Hindustan Antibiotics Bulletin
P Ellaiah, B Srinivasulu


A new strain of Streptomyces fradiae, isolated and identified in our laboratory, was found to be a potential producer of protease enzyme. An enzyme yield of 285 P.U./ml. was obtained prior to optimization in a synthetic medium containing potato starch, potassium nitrate and trace salts by shake flask method. The carbon and nitrogen compounds play prominent role in the protease production. The maximum enzyme yield of 930 P.U./ml. (about 3-fold increase) was obtained with all optimum parameters such as pH. 7.0, with 3% jowar starch, 0.5% tryptone, 28 degrees C incubation temperature, with 1:20 medium to flask volume ratio and with 48 hrs. inoculum.

Related Concepts

Potassium nitrate monohydrate
Hydrogen-Ion Concentration
Potassium Compounds

Trending Feeds


Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Lipidomics & Rhinovirus Infection

Lipidomics can be used to examine the lipid species involved with pathogenic conditions, such as viral associated inflammation. Discovered the latest research on Lipidomics & Rhinovirus Infection.

Alzheimer's Disease: MS4A

Variants within the membrane-spanning 4-domains subfamily A (MS4A) gene cluster have recently been implicated in Alzheimer's disease in genome-wide association studies. Here is the latest research on Alzheimer's disease and MS4A.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Torsion Dystonia

Torsion dystonia is a movement disorder characterized by loss of control of voluntary movements appearing as sustained muscle contractions and/or abnormal postures. Here is the latest research.

Generating Insulin-Secreting Cells

Reprogramming cells or using induced pluripotent stem cells to generate insulin-secreting cells has significant therapeutic implications for diabetics. Here is the latest research on generation of insulin-secreting cells.

Central Pontine Myelinolysis

Central Pontine Myelinolysis is a neurologic disorder caused most frequently by rapid correction of hyponatremia and is characterized by demyelination that affects the central portion of the base of the pons. Here is the latest research on this disease.

Epigenome Editing

Epigenome editing is the directed modification of epigenetic marks on chromatin at specified loci. This tool has many applications in research as well as in the clinic. Find the latest research on epigenome editing here.