Jan 1, 1988

Production of interferon by leukocytes from patients with atopic and nonatopic asthma

Archivum Immunologiae Et Therapiae Experimentalis
R JankowskaJ Zielińska-Jenczylik


Investigations were carried out on 62 patients with atopic and nonatopic asthma and 70 normal individuals. Leukocytes isolated according to the method of Mogensen and Cantell, were induced for interferon production with Newcastle virus, H strain for 24 h at 37 degrees C in a tube culture placed in rolling drum. Interferon was assayed in the culture of human fibroblasts (HAT). Leukocytes from patients with both types of asthma had reduced interferon-inducing activity. At acute viral infection, a transient increase of interferon titer was observed. The titer, however, never reached the values of interferon induced in leukocytes from healthy individuals.

  • References
  • Citations


  • We're still populating references for this paper, please check back later.
  • References
  • Citations


  • This paper may not have been cited yet.

Mentioned in this Paper

Dermatitis, Atopic
Upper Respiratory Infections
Eye Infections, Viral
Orthomyxoviridae Infections

About this Paper

Related Feeds

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.


This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. Discover the latest research on atopic dermatitis here.

Related Papers

Archivum Immunologiae Et Therapiae Experimentalis
H SzalatyJ Zielińska-Jenczylik
Archivum Immunologiae Et Therapiae Experimentalis
A Sypuła, J Zielińska-Jenczylik
Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
Meredith C McCormackCenter for Childhood Asthma in the Urban Environment
© 2020 Meta ULC. All rights reserved