PMID: 3754250Feb 1, 1986Paper

Production of novel antibiotic, dopsisamine, by a new subspecies of Nocardiopsis mutabilis with multiple antibiotic resistance

The Journal of Antibiotics
A TakahashiH Umezawa

Abstract

An actinomycete isolate designated as TS-1980 with multiple resistance to aminoglycoside antibiotics was found to produce novel antibiotics. The strain showed taxonomic features identical to the type strain of Nocardiopsis mutabilis except for the temperature range for growth and the utilization of mannitol and raffinose. Based on the capability of growing at lower temperature range, the strain was named N. mutabilis subsp. cryophilis subsp. nov. Physico-chemical and biological characterization of a purified antibiotic revealed its novel polyamine-type nature with a broad antimicrobial activity. The antibiotic was named dopsisamine.

Citations

Jul 19, 2012·World Journal of Microbiology & Biotechnology·Adel AouicheAhmed Lebrihi
May 27, 2017·World Journal of Microbiology & Biotechnology·Yamina Hadj Rabia-BoukhalfaVéronique Eparvier
Nov 6, 2015·Natural Product Research·Ming-Wei SunChun-Hua Lu
Jan 1, 1991·Critical Reviews in Biotechnology·C M Franco, L E Coutinho
Sep 16, 2015·Journal of Applied Microbiology·T BennurV Javdekar

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