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Products of the Parkinson's-disease related glyoxalase DJ-1, D-lactate and glycolate, support mitochondrial membrane potential and neuronal survival

bioRxiv

Jul 4, 2014

Yusuke ToyodaTeymuras V. Kurzchalia

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Abstract

Parkinson's disease is associated with mitochondrial decline in dopaminergic neurons of the substantia nigra. One of the genes, DJ- 1/PARK7, linked with the onset of Parkinson’s disease, belongs to a novel glyoxalase family and influences mitochondrial activity. It has been assumed that...read more

Mentioned in this Paper

Paraquat
Parkinson Disease
Cellular Stress
Glycolic acid
Acids
Glycolates
Membrane Potential, Mitochondrial
PARK7 gene
Biochemical Pathway
Mitochondrial Inheritance
6
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  • Products of the Parkinson's-disease related glyoxalase DJ-1, D-lactate and glycolate, support mitochondrial membrane potential and neuronal survival

    bioRxiv

    Jul 4, 2014

    Yusuke ToyodaTeymuras V. Kurzchalia

    PMID: 990006916

    DOI: 10.1101/006916

    Abstract

    Parkinson's disease is associated with mitochondrial decline in dopaminergic neurons of the substantia nigra. One of the genes, DJ- 1/PARK7, linked with the onset of Parkinson’s disease, belongs to a novel glyoxalase family and influences mitochondrial activity. It has been assumed that...read more

    Mentioned in this Paper

    Paraquat
    Parkinson Disease
    Cellular Stress
    Glycolic acid
    Acids
    6

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