Profile and variables related to antipsychotic consumption according to dementia subtypes

International Psychogeriatrics
Laia Calvó-PerxasRegistry of Dementias of Girona Study

Abstract

Antipsychotics (APs) are usually prescribed to deal with behavioral and psychological symptoms of dementia (BPSD), but poor outcomes, important side effects, and high mortality risk should be addressed. The aim of this study was to estimate the prevalence of AP consumption in patients with dementia, and to describe and compare the sociodemographic and clinical characteristics of patients consuming APs. This was a cross-sectional study using 1,894 cases of dementia registered from 2007 to 2009 by the Registry of Dementias of Girona (ReDeGi), which is a population-based passive surveillance system of dementia diagnoses. APs were categorized according to the anatomical therapeutic chemical (ATC) classification, and grouped as typical antipsychotics (TAPs) or atypical antipsychotics (AAPs). Binary logistic regression analyses were used to detect the predictors of AP use as well as the variables associated with TAP or AAP prescription. APs were used in 29.6% of the cases, with Parkinsonian syndromes (PSd) being the subtype of dementia with the highest AP prescription (50.6% of the patients with PSd). AAPs were mainly prescribed in all subtypes of dementia, except in vascular dementia (VaD) and PSd, where no preference in TAP or AAP ...Continue Reading

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Citations

Nov 28, 2012·European Journal of Clinical Pharmacology·Pilar Avila-CastellsUNKNOWN Registry Dementia of Girona Study Group
Mar 19, 2014·Journal of the American Medical Directors Association·Laia Calvó-PerxasUNKNOWN Registry of Dementias of Girona Study Group (ReDeGi Study Group)
Feb 16, 2016·Neurología : publicación oficial de la Sociedad Española de Neurología·O Turró-GarrigaR Sánchez-Valle
Oct 10, 2015·The British Journal of Psychiatry : the Journal of Mental Science·Marjaana KoponenSirpa Hartikainen
Feb 27, 2015·Archives of Gerontology and Geriatrics·O Turró-GarrigaUNKNOWN Registry of Dementia of Girona Study Group (ReDeGi Study Group)
Feb 18, 2017·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Julia KirkhamDallas Seitz
May 15, 2015·American Journal of Alzheimer's Disease and Other Dementias·Robert D NeumannRichard Klassen
Nov 21, 2019·Aging & Mental Health·Adrie A J GerritsenRaymond T C M Koopmans

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