PMID: 9174257May 20, 1997Paper

Profile of glutamylated tubulin expression during cerebellar granule cell development in vitro

Brain Research. Developmental Brain Research
S A Przyborski, M A Cambray-Deakin

Abstract

The developmental regulation of tubulin and several of its posttranslational modifications was examined during the differentiation of rat cerebellar granule cells in vitro. In particular, we have noted that the glutamylation of alpha- and beta-tubulin subunits varies during development and becomes more prominent in differentiating neuronal processes. These results indicate that glutamylation of tubulin may be important in the stabilization of microtubules during the maturation of the neuronal cytoskeleton.

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Citations

Jan 30, 2008·Toxicological Sciences : an Official Journal of the Society of Toxicology·Loretta L CollinsLisa A Opanashuk
Mar 3, 2009·Journal of Neurochemistry·Nobuyuki FukushimaToshifumi Tsujiuchi
Aug 6, 2015·Developmental Neurobiology·Daniel P DeverLisa A Opanashuk
Dec 6, 2005·Mechanisms of Development·Valery Krizhanovsky, Nissim Ben-Arie
Aug 12, 2006·The Journal of Biological Chemistry·Koji IkegamiMitsutoshi Setou
Dec 17, 2020·Developmental Neurobiology·Marie-Jo MoutinAnnie Andrieux

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