PMID: 11921675Mar 30, 2002Paper

Profile of the Nigerian sickle cell anaemia patients above 30 years of age

The Central African Journal of Medicine
A Yetunde, C C Anyaegbu

Abstract

To examine the haematological profiles of patients with sickle cell anaemia above the age of 30 years. Prospective cross sectional study. Department of Haematology University College Hospital, Ibadan, Nigeria. 98 patients with sickle cell anaemia above the age of 30 years. Clinical and haematological profiles of the patients. There were 75 females and 23 males. The steady state packed cell volume was 21 to 28% with a median of 24% Haemoglobin F (HbF) level in 33 patients was greater than 3% but less than 5%. Thirty six patients had a HbF which was greater than 5% but less than 10%. Twenty three patients had a HbF level which was greater than 10% but less than 15%. Five patients had a HbF level greater than 15% and only one patient had a HbF level of 22%. The severe complications of sickle cell anaemia were not observed in 87 patients (88.8%), though some age related complications like Grade 4 ischaemic necrosis of the femoral head, chronic inflammatory liver changes and ophthalmic complications were observed. Eighty six patients had never had a blood transfusion, while 76 had never been admitted into hospital. Thirty four patients had a mild to moderate degree of splenomegaly while 64 patients had mild to moderate degree of hep...Continue Reading

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