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Profiling direct mRNA-microRNA interactions using synthetic biotinylated microRNA-duplexes

bioRxiv

May 22, 2014

Shivangi Wani, Nicole Cloonan

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Abstract

MicroRNAs (miRNAs) are predominantly negative regulators of gene expression that act through the RNA-induced Silencing Complex (RISC) to suppress the translation of protein coding mRNAs. Despite intense study of these regulatory molecules, the specific molecular functions of most miRNAs...read more

Mentioned in this Paper

Gene Expression
RNA-Induced Silencing Complex
Company (Organization)
Insulin, biotinyl-
Profile (Lab Procedure)
Genome
Genome-Wide Association Study
SCPEP1 gene
MicroRNAs
Gene Silencing by RNA
4
61
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  • Profiling direct mRNA-microRNA interactions using synthetic biotinylated microRNA-duplexes

    bioRxiv

    May 22, 2014

    Shivangi Wani, Nicole Cloonan

    PMID: 990005439

    DOI: 10.1101/005439

    Abstract

    MicroRNAs (miRNAs) are predominantly negative regulators of gene expression that act through the RNA-induced Silencing Complex (RISC) to suppress the translation of protein coding mRNAs. Despite intense study of these regulatory molecules, the specific molecular functions of most miRNAs...read more

    Mentioned in this Paper

    Gene Expression
    RNA-Induced Silencing Complex
    Company (Organization)
    Insulin, biotinyl-
    Profile (Lab Procedure)
    4
    61

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