Profiling of the reactive oxygen species-related ecotoxicity of CuO, ZnO, TiO2, silver and fullerene nanoparticles using a set of recombinant luminescent Escherichia coli strains: differentiating the impact of particles and solubilised metals

Analytical and Bioanalytical Chemistry
Angela IvaskAnne Kahru

Abstract

We propose a novel combination of high-throughput luminescent bacterial tests for the evaluation of the reactive oxygen species (ROS)-generating potential of engineered nanoparticles (eNPs) and the role of solubilised metal ions in this process. The set of tests consists of differently engineered recombinant Escherichia coli strains: (1) a new sensor strain, which bioluminescence is induced by superoxide anions; (2) six recombinant E. coli strains (superoxide dismutase (sod) single, double and triple mutants and a respective wild-type strain), transformed with luxCDABE genes responding to toxic compounds by decreasing their luminescence; and (3) three strains in which bioluminescence is specifically induced by bioavailable metals (Cu, Zn and Ag). The applicability of this battery of tests in profiling oxidative potential of eNPs was evaluated on nTiO(2), nCuO, nZnO and nAg (25, 30, 70 and <100 nm, respectively) NPs and fullerenes. As controls for the size or solubility, the bulk formulations (bTiO(2), bCuO and bZnO) and soluble salts (ZnSO(4), CuSO(4) and AgNO(3)) were also analysed. Bacterial toxicity tests showed that nCuO was four-fold more toxic, and nAg was 15-fold more toxic to triple sod mutant than to wild type (2-h EC(...Continue Reading

References

Mar 1, 1977·Journal of Bacteriology·H M Hassan, I Fridovich
Jul 1, 1987·Journal of Bacteriology·J A Imlay, S Linn
Jan 1, 1987·Journal of Cell Science. Supplement·S Linn, J A Imlay
Mar 17, 1997·Mutation Research·T Kimura, H Nishioka
Oct 14, 2003·American Journal of Physiology. Lung Cellular and Molecular Physiology·D M BrownV Stone
Mar 1, 1996·Analytical and Bioanalytical Chemistry·I VillaescusaJ C Murat
Jun 14, 2005·American Journal of Physiology. Lung Cellular and Molecular Physiology·Anna A ShvedovaPaul Baron
Feb 4, 2006·Science·Andre NelNing Li
Apr 11, 2006·Journal of Proteome Research·Chun-Nam LokChi-Ming Che
Jul 21, 2006·The Journal of Physical Chemistry. B·Guifen FuChhiu-Tsu Lin
Aug 15, 2006·Environmental Science & Technology·Tobias J BrunnerWendelin J Stark
Aug 17, 2006·Environmental Science and Pollution Research International·Kerstin Hund-Rinke, Markus Simon
Apr 19, 2007·Environmental Science & Technology·Jiasong FangPedro J J Alvarez
Sep 22, 2007·Biomaterials·Zoran MarkovicVladimir Trajkovic
Jan 22, 2008·Analytica Chimica Acta·Stefano GirottiElisabetta Maiolini
Apr 11, 2008·Toxicology in Vitro : an International Journal Published in Association with BIBRA·M MortimerA Kahru
Jun 6, 2008·Environmental Toxicology·C BlaiseP Eullaffroy
Jul 9, 2008·Environmental Science & Technology·Nicole C Mueller, Bernd Nowack
Aug 20, 2008·Chemical Research in Toxicology·Hanna L KarlssonLennart Möller
Nov 29, 2008·The Science of the Total Environment·Villem AruojaAnne Kahru
Dec 17, 2008·Environmental Toxicology and Chemistry·Ilona VelzeboerDik Van de Meent
Feb 3, 2009·Environmental Pollution·Wei JiangBaoshan Xing
Feb 14, 2009·The Science of the Total Environment·Xiaoke HuHuey-Min Hwang
Jun 3, 2009·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Kaja KasemetsAnne Kahru
Jul 17, 2009·Environmental Science & Technology·Léna BrunetMark R Wiesner
Aug 29, 2009·Nature·Thomas Hartung, Costanza Rovida
Sep 8, 2009·Toxicology·Anne Kahru, Henri-Charles Dubourguier
Oct 6, 2009·Environmental Pollution·I BlinovaA Kahru
Jan 29, 2010·Toxicology·Kai SavolainenGerhard Kasper

❮ Previous
Next ❯

Citations

Aug 27, 2013·Biosensors & Bioelectronics·Jonathan S Mcquillan, Andrew M Shaw
Nov 15, 2012·Accounts of Chemical Research·Anne Kahru, Angela Ivask
Mar 16, 2011·Chemical Reviews·Morteza MahmoudiSophie Laurent
Jun 30, 2011·Environmental Science & Technology·Monika MortimerAnne Kahru
Mar 23, 2012·Environmental Science & Technology·Zhenyu WangBaoshan Xing
Sep 30, 2014·Journal of Hazardous Materials·Xavier BellangerChristophe Merlin
Dec 3, 2014·Journal of Hazardous Materials·Nathalie AdamRonny Blust
Dec 29, 2012·Journal of Hazardous Materials·Min TuZhonghong Gao
Jul 30, 2015·BioMed Research International·Ludmila V EfremovaDmitry G Deryabin
Mar 26, 2011·Journal of Hazardous Materials·Mario Luna-delRiscoHenri-Charles Dubourguier
Jan 29, 2016·Advanced Pharmaceutical Bulletin·Javad Khalili FardMohammad Ali Eghbal
Dec 14, 2011·Journal of Applied Toxicology : JAT·Go HasegawaYoko Ishihara
Apr 5, 2013·Environmental Toxicology and Chemistry·Yu YangPedro J J Alvarez
Aug 8, 2015·Nanomedicine·Maqusood AhamedSalman A Alrokayan
May 2, 2015·The Science of the Total Environment·Nathalie AdamRonny Blust
Sep 22, 2012·Environmental Pollution·Hongbo MaStephen A Diamond
Dec 30, 2014·Environmental Science and Pollution Research International·Aridane G GonzálezJean-Luc Rols
Jan 4, 2015·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Sylvie Gaillet, Jean-Max Rouanet
Aug 12, 2016·Toxicology in Vitro : an International Journal Published in Association with BIBRA·Aleksandr KäkinenOlesja M Bondarenko
Aug 27, 2016·Applied Biochemistry and Biotechnology·Hira ZafarMuhammad Zia
Apr 26, 2017·Environmental Toxicology and Chemistry·Andrew BarrickCatherine Mouneyrac
Jul 21, 2015·Chemical Society Reviews·Kristen P MillerAlan W Decho
Jul 29, 2011·Nanomedicine·Matthew Charles StensbergMaría Soledad Sepúlveda

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.