Profound increase in longitudinal displacements of the porcine carotid artery wall can take place independently of wall shear stress: a continuation report

Ultrasound in Medicine & Biology
Asa Rydén AhlgrenMagnus Cinthio

Abstract

The mechanisms underlying longitudinal displacements of the arterial wall, that is, displacements of the wall layers along the artery, and the resulting intramural shear strain remain largely unknown. We have already found that these displacements undergo profound changes in response to catecholamines. Wall shear stress, closely related to wall shear rate, represents the viscous drag exerted on the vessel wall by flowing blood. The aim of the work described here was to study possible relations between the wall shear rate and the longitudinal displacements. We investigated the carotid arteries of five anesthetized pigs in different hemodynamic situations using in-house developed non-invasive ultrasound techniques. The study protocol included administration of epinephrine, norepinephrine and β-blockade (metoprolol). No significant correlation between longitudinal displacement of the intima-media complex and wall shear rate was found. This result suggests that one or multiple pulsatile forces other than wall shear stress are also working along arteries, strongly influencing arterial wall behavior.

References

Jan 1, 1989·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·J S Simonson, N B Schiller
Oct 26, 2005·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Magnus CinthioKjell Lindström
Feb 14, 2006·American Journal of Physiology. Heart and Circulatory Physiology·Magnus CinthioKjell Lindström
Nov 23, 2006·Ultrasound in Medicine & Biology·Piero TortoliKumar V Ramnarine
May 26, 2007·Journal of Applied Physiology·Wei ZhangGhassan S Kassab
Oct 15, 2008·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·S Hodis, M Zamir
Nov 28, 2009·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Piero TortoliStefano Ricci
Mar 2, 2010·American Journal of Physiology. Heart and Circulatory Physiology·John R Halliwill, Christopher T Minson
Apr 7, 2010·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·S Hodis, M Zamir
Aug 31, 2010·Ultrasound in Medicine & Biology·Magnus CinthioHans W Persson
Jul 7, 2011·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·S Hodis, M Zamir
Nov 22, 2011·Journal of the Mechanical Behavior of Biomedical Materials·S Hodis, M Zamir
Oct 16, 2012·Ultrasound in Medicine & Biology·Tim IdzengaChris L de Korte
Mar 6, 2013·Mathematical Biosciences and Engineering : MBE·Martina Bukač, Sunčica Čanić

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Citations

Dec 27, 2015·Ultrasound in Medicine & Biology·Canxing XuKirk W Beach
Jun 5, 2016·Ultrasound in Medicine & Biology·Jimmy TatStella S Daskalopoulou
May 18, 2016·IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control·Enrico BoniPiero Tortoli
Oct 8, 2017·Experimental Physiology·Jason S AuMaureen J MacDonald
Mar 26, 2021·Clinical Physiology and Functional Imaging·Yuxiang ZhuÅsa Rydén Ahlgren

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