Progesterone levels on the hCG day and outcomes in vitro fertilization in women with polycystic ovary syndrome.

Journal of Assisted Reproduction and Genetics
Cuiying PengGuangxiu Lu

Abstract

The purpose of this study was to determine the incidence of premature luteinization in patients with polycystic ovary syndrome and compared the main determinants of success in in-vitro fertilization in PCOS patients with and without premature luteinization. Retrospective analysis of 180 PCOS women of Chinese Han origin with infertility who underwent controlled ovarian hyperstimulation (COH) with an exogenous gonadotropin/GnRH antagonist protocol. Hormone levels on the hCG day and IVF outcomes were assessed. The incidence of premature luteinization was 23.3 %. Compared with PCOS patients without premature luteinization, PCOS patients with premature luteinization(PL) had a higher number of oocytes retrieved (18.20 ± 6.6 vs 15.08 ± 7.3, p = 0.037) and a higher fertilization rate (72.9 ± 1.9 vs63.1 ± 2.3, p = 0.033), but clinical pregnancy rates were no statistical significance (53.3 vs 56.0, p = 0.836). Though the implantation rate was higher in no premature luteinization patients, but the difference was not statistically significant (37.7 vs 30.3, p = 0.115). The PCOS patients with premature luteinization had a higher fertilization rate and high number of oocytes retrieved, and the similar implantation rate and clinical PRs as PC...Continue Reading

References

Sep 24, 1998·The Journal of Clinical Endocrinology and Metabolism·E S KnochenhauerR Azziz
Jun 12, 2002·Fertility and Sterility·Fernando Ovalle, Ricardo Azziz
Jun 6, 2003·The Journal of Clinical Endocrinology and Metabolism·Rose C ChristianLorraine A Fitzpatrick
Dec 23, 2003·Human Reproduction·UNKNOWN Rotterdam ESHRE/ASRM-Sponsored PCOS consensus workshop group
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Feb 24, 2010·Journal of Assisted Reproduction and Genetics·Aboubakr M Elnashar

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Citations

Jan 15, 2016·Reproductive Sciences·Shi XieYanping Li
Feb 22, 2018·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Ai Ling LiuCui Ying Peng
Jul 28, 2018·Journal of Assisted Reproduction and Genetics·Apostolos KaponisGeorge Decavalas

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