PMID: 6979236Jun 1, 1982Paper

Prognosis of asymptomatic or mildly symptomatic patients with coronary artery disease

The American Journal of Cardiology
K M KentS E Epstein

Abstract

One hundred forty-seven asymptomatic or mildly symptomatic patients with coronary artery disease, who did not have significant left main coronary occlusion and had an ejection fraction greater than 20 percent, were followed up prospectively for 6 to 67 months (average 25). Significant obstruction of one coronary artery was present in 28 percent of patients, of two coronary arteries in 31 percent and of three coronary arteries in 41 percent. Ejection fraction was 55 percent or greater in 69 percent of patients. During the follow-up there were eight deaths (annual mortality rate 3 percent for the entire group, 1.5 percent for patients with single and double vessel disease but 6 percent for those with triple vessel disease). Better definition of high and low risk subgroups of patients with three vessel disease was accomplished with exercise testing. Despite a history of mild symptoms, 25 percent of the patients with triple vessel disease exhibited poor exercise capacity on exercise testing after administration of beta adrenoceptor blocking agents and nitrates was discontinued; of these, 40 percent either died (20 percent) or had progressive symptoms requiring operation (20 percent) (annual mortality rate 9 percent). Of the patient...Continue Reading

Citations

Jun 11, 1991·Clinical Cardiology·S D Clements, S Gatlin
Jun 1, 1996·Clinical Cardiology·R A O'Rourke
May 1, 1988·Cardiovascular Drugs and Therapy·P R Lichtlen
May 1, 1988·Cardiovascular Drugs and Therapy·W RutishauserP Roy
Nov 1, 1994·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·G MazzottaR O Bonow
Jan 29, 1988·The American Journal of Cardiology·P F Cohn
Mar 1, 1995·Progress in Cardiovascular Diseases·J KupersmithJ Gardiner
Jul 17, 1998·Trends in Pharmacological Sciences·P FerdinandyG F Baxter
Jan 1, 1983·Journal of the American College of Cardiology·F L Meijler
Mar 1, 1983·Journal of the American College of Cardiology·P F Cohn
Aug 1, 1984·Journal of the American College of Cardiology·R E PattersonS R Goldstein
Mar 1, 1984·Journal of the American College of Cardiology·D A WeinerF Tristani
Jun 1, 1984·Journal of the American College of Cardiology·J A Ambrose
Oct 1, 1984·Journal of the American College of Cardiology·N L Coplan, J A Ambrose
Nov 1, 1986·Journal of the American College of Cardiology·D D Waters
Oct 1, 1986·Journal of the American College of Cardiology·P F CohnE J Brown
Feb 1, 1987·Journal of the American College of Cardiology·C FalconeG Specchia
Jul 1, 1997·Journal of the American College of Cardiology·D Tzivoni, S Maybaum
Aug 20, 1983·British Medical Journal·M C Petch
Mar 1, 1992·Journal of Neurology, Neurosurgery, and Psychiatry·G J Hankey, C P Warlow
Nov 1, 1991·American Heart Journal·C K MorrisV F Froelicher
Mar 15, 1983·The American Journal of Cardiology·A Selzer
Aug 15, 1986·The American Journal of Cardiology·P F Cohn
Sep 13, 1985·The American Journal of Medicine·P F Cohn
Jul 1, 1992·American Heart Journal·N L Coplan, I D Wallach
Apr 1, 1984·Clinical Cardiology·J W Hurst
Apr 21, 1988·The American Journal of Cardiology·S SternD Tzivoni
Mar 1, 1984·Stroke; a Journal of Cerebral Circulation·H P AdamsH Mazuz

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