Prognosis of mild cognitive impairment syndrome: data from a two-year clinical follow-up study

Neuroscience and Behavioral Physiology
S I GavrilovaG I Korovaĭtseva

Abstract

The psychopathological structure and prognostic significance of mild cognitive impairment syndrome (MCI) were studied in a two-year prospective study of randomized cohorts of elderly subjects whose mental state corresponded to the criteria for MCI. A total of 40 patients aged from 50 to 80 years were studied. Patients underwent clinical history-taking, neuropsychological, psychometric, and genetic investigations (genotyping for ApoE), as well as brain imaging studies. The psychopathological structure and psychometric characteristics of MCI syndrome are presented. Clinical and genetic factors with prognostic significance are identified.

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Citations

Apr 23, 2013·The Tohoku Journal of Experimental Medicine·Kyoko YamamotoToshio Fujioka
Oct 17, 2014·Journal of Geriatric Psychiatry and Neurology·Sean AmodeoKenneth I Shulman

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