Prognosis of small thyroid cancer in patients with Graves' disease

The British Journal of Surgery
S KikuchiH Kawamoto

Abstract

To find the best ways to follow up patients with small thyroid cancer (STC; 1 cm or less in diameter) and concomitant Graves' disease, this study examined whether such patients had the same excellent prognosis as those with STC without Graves' disease. Between 1970 and 1996, 2199 patients were diagnosed as having STC by pathology after thyroidectomy. Of those, 509 patients (33 males and 476 females, mean age 43.5 years) underwent thyroidectomy for Graves' disease. Control patients with STC without Graves' disease were matched for age, sex, treatment year and tumour size (33 males and 476 females, mean age 44.0 years). Patients with STC and Graves' disease had a longer disease-free survival than those with STC alone (99 and 93 per cent at 20 years' follow-up, respectively; P < 0.001). The Cox's proportional hazard analysis showed that concomitant Graves' disease and age at surgery are more significant factors for predicting disease-free survival than surgical procedures. Patients who undergo thyroidectomy for Graves' disease and are found to have STC have an excellent prognosis and longer disease-free survival than patients with STC alone.

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Citations

Apr 23, 2011·Thyroid : Official Journal of the American Thyroid Association·Rebecca S Bahn ChairUNKNOWN American Association of Clinical Endocrinologists
Jun 29, 2013·Metabolism: Clinical and Experimental·Athanasios D AnastasilakisStergios Papachatzopoulos
Oct 22, 2014·Endocrine Pathology·Shuanzeng WeiVirginia A LiVolsi
Aug 16, 2016·Thyroid : Official Journal of the American Thyroid Association·Douglas S RossMartin A Walter
Jan 30, 2015·Arquivos brasileiros de endocrinologia e metabologia·Abbas Ali TamBekir Çakır
May 24, 2007·Ophthalmic Plastic and Reconstructive Surgery·Jin Sook YoonSang Yeul Lee
May 23, 2018·The Journal of Clinical Endocrinology and Metabolism·Suzanne P MacFarlandSogol Mostoufi-Moab
Aug 15, 2019·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Poemlarp MekraksakitRaynald Samoa
Jun 28, 2011·Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists·Rebecca S BahnUNKNOWN American Association of Clinical Endocrinologists
May 18, 2013·Arquivos brasileiros de endocrinologia e metabologia·Ana Luiza MaiaUNKNOWN Brazilian Society of Endocrinology and Metabolism
Oct 15, 2020·World Journal of Surgical Oncology·Hyungju Kwon, Byung-In Moon

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