Prognostic accuracy of the Hamilton Early Warning Score (HEWS) and the National Early Warning Score 2 (NEWS2) among hospitalized patients assessed by a rapid response team

Critical Care : the Official Journal of the Critical Care Forum
Shannon M FernandoKwadwo Kyeremanteng

Abstract

Rapid response teams (RRTs) respond to hospitalized patients experiencing clinical deterioration and help determine subsequent management and disposition. We sought to evaluate and compare the prognostic accuracy of the Hamilton Early Warning Score (HEWS) and the National Early Warning Score 2 (NEWS2) for prediction of in-hospital mortality following RRT activation. We secondarily evaluated a subgroup of patients with suspected infection. We retrospectively analyzed prospectively collected data (2012-2016) of consecutive RRT patients from two hospitals. The primary outcome was in-hospital mortality. We calculated the number needed to examine (NNE), which indicates the number of patients that need to be evaluated in order to detect one future death. Five thousand four hundred ninety-one patients were included, of whom 1837 (33.5%) died in-hospital. Mean age was 67.4 years, and 51.6% were male. A HEWS above the low-risk threshold (≥ 5) had a sensitivity of 75.9% (95% confidence interval (CI) 73.9-77.9) and specificity of 67.6% (95% CI 66.1-69.1) for mortality, with a NNE of 1.84. A NEWS2 above the low-risk threshold (≥ 5) had a sensitivity of 84.5% (95% CI 82.8-86.2), and specificity of 49.0% (95% CI: 47.4-50.7), with a NNE of 2....Continue Reading

References

Feb 7, 1998·Medical Care·A ElixhauserR M Coffey
Mar 1, 2002·Statistics in Medicine·Todd A AlonzoChaya S Moskowitz
Apr 2, 2008·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Alan D BaxterRakesh Patel
Aug 3, 2010·Resuscitation·Paolo CalzavaccaRinaldo Bellomo
Jan 16, 2013·Critical Care Medicine·Gabriella JäderlingDavid Konrad
Feb 5, 2013·Resuscitation·Daryl JonesDavid Story
Mar 6, 2013·Annals of Internal Medicine·Bradford D WintersSydney M Dy
Jun 27, 2013·Current Opinion in Critical Care·Daryl JonesJohn Welch
Oct 9, 2014·Annals of the American Thoracic Society·M E Beth SmithChristopher G Slatore
Jan 7, 2015·Critical Care Medicine·Matthew M ChurpekDana P Edelson
Mar 5, 2015·Anaesthesia and Intensive Care·G CrossD Jones
Jun 14, 2015·Critical Care : the Official Journal of the Critical Care Forum·Ritesh MaharajJulia Wendon
Aug 14, 2015·Critical Care : the Official Journal of the Critical Care Forum·Santiago Romero-BrufauMark Liebow
Oct 7, 2015·International Journal of Health Care Quality Assurance·Gary B SmithPaul E Schmidt
Feb 24, 2016·JAMA : the Journal of the American Medical Association·Christopher W SeymourDerek C Angus
Feb 24, 2016·JAMA : the Journal of the American Medical Association·Mervyn SingerDerek C Angus
Feb 28, 2016·Intensive Care Medicine·Audrey De JongSamir Jaber
May 20, 2016·Current Infectious Disease Reports·Peter ChanDaryl Jones
Jul 5, 2016·Chest·Poushali BhattacharjeeMatthew M Churpek
Mar 16, 2017·Critical Care : the Official Journal of the Critical Care Forum·Christian P SubbeRinaldo Bellomo
Feb 7, 2018·Critical Care Medicine·Shannon M FernandoKwadwo Kyeremanteng
Mar 15, 2018·Critical Care : the Official Journal of the Critical Care Forum·Shannon M FernandoKwadwo Kyeremanteng
May 1, 2018·Journal of Critical Care·Peter M ReardonKwadwo Kyeremanteng
May 20, 2018·Resuscitation·Patrick G LyonsMatthew M Churpek
Jul 7, 2018·Critical Care : the Official Journal of the Critical Care Forum·Shannon M FernandoKwadwo Kyeremanteng

❮ Previous
Next ❯

Citations

Dec 10, 2019·British Medical Bulletin·Eleanor MitchellAnthony Roberts
Apr 10, 2020·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Samuel Finnikin, Veronica Wilke
Jul 18, 2020·The European Respiratory Journal·Guohui FanBin Cao
May 24, 2020·Internal and Emergency Medicine·Lorenzo BertolinoEmanuele Durante-Mangoni
Jul 14, 2020·Acta Anaesthesiologica Scandinavica·In-Ae SongDa-Yun Lee
Aug 22, 2020·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Francisco Martín-RodríguezRaúl López-Izquierdo
Sep 10, 2020·Disaster Medicine and Public Health Preparedness·Hai HuYanru Qiu
Oct 24, 2020·International Journal of Clinical Practice·Raúl López-IzquierdoCarlos Del Pozo Vegas

❮ Previous
Next ❯

Software Mentioned

R
NEWS2
SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.