Prognostic analysis of advanced non small cell lung cancer treated by sequential chemo-radiation therapy combined with traditional Chinese medicine: a report of 54 cases

Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine
Ming-Quan HanZhao-Ying Sheng

Abstract

To evaluate the influence of fewer courses and prolonged intervals of chemotherapy on survival rate of advanced non small cell lung cancer (NSCLC) patients treated by sequential chemo-radiation therapy combined with traditional Chinese medicine (TCM). From Jan. 2000 to Dec. 2001, 54 untreated advanced NSCLC patients (2 stage IIIa, 18 stage IIIb, 34 stage IV) were treated by sequential chemo-radiation therapy combined with TCM. The courses of chemotherapy were reduced and the intervals of chemotherapy were longer than that of the standard regimen. The efficacy and survival rate were documented and the prognostic factors were analyzed. Complete remission (CR) was observed in 1 case and partial remission (PR) in 20 cases. The overall objective response rate was 40.4%. Median survival was 15.3 months, 1-, 2- and 3-year survival rate were 53.7%, 28.9% and 9.6% respectively. The median survival of stage III and IV were 21.8 months and 12.5 months respectively. The 1-, 2-, and 3-year survival rates of stage III were 65.0%, 49.5%, 24.7% and that of stage IV were 47.0%, 23.3%, 0%, respectively. The quality of life was improved in most of the patients. Cox's proportional hazards regression showed that improved quality of life and treatme...Continue Reading

References

Jan 1, 1992·Journal of the National Cancer Institute·T Le ChevalierJ Y Douillard
Feb 13, 2001·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·A MontazeriC R Gillis
Feb 13, 2003·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·F CardenalR Rosell
Feb 25, 2003·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M J MillwardJ F Bishop

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Citations

Sep 2, 2004·Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine·Wei-Ming FangJian-Yuan Zhou
Jul 17, 2007·Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine·Su-fang ZhangZhe Chen
Mar 18, 2016·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Woung-Ru TangYue-Cune Chang
Jun 19, 2014·Phytomedicine : International Journal of Phytotherapy and Phytopharmacology·G H DaiF Yang
May 2, 2013·The Cochrane Database of Systematic Reviews·Jian Ping LiuFrancesco Cardini

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