Abstract
The aim of this study was to define the risk ratios of the late-infancy magnetic resonance imaging pattern for long-term outcome in term infants with perinatal asphyxia. We evaluated 65 term infants with perinatal asphyxia and performed magnetic resonance imaging examinations between 4-12 months of age. Magnetic resonance imaging scans were classified as follows: (1) periventricular leukomalacia in 21 (32%) infants, (2) marked cortical atrophy in 17 (26%) infants, (3) multicystic encephalomalacia in 10 (15%) infants, (4) deep gray matter involvement in 8 (12%) infants, (5) focal cortical involvement in 6 (9%) infants, (6) myelination delay in 3 (5%) infants. The overall outcome was favorable in 19 (29%) of 65 infants. Infants with diffuse cortical involvement (multicystic encephalomalacia and marked cortical atrophy) are four times (odds ratio: 4.4 and 4.1 respectively) more likely to attain the unfavorable outcome than the infants with other patterns of magnetic resonance imaging. Infants with focal cortical involvement had relatively favorable outcome in 60% of the cases. In conclusion, it appears that the overall outcome of infants with perinatal asphyxia correlated well with the magnetic resonance imaging patterns obtained ...Continue Reading
References
Aug 1, 1991·Acta paediatrica Scandinavica·K YokochiS Fujimoto
Nov 1, 1990·The Journal of Pediatrics·P ByrneM Piper
Mar 1, 1989·Clinical Radiology·L S de VriesG M Bydder
Mar 1, 1989·AJR. American Journal of Roentgenology·O FlodmarkM G Norman
Sep 1, 1988·Radiology·L L BakerD R Enzmann
Aug 1, 1995·European Journal of Obstetrics, Gynecology, and Reproductive Biology·H H de Haan, T H Hasaart
Oct 1, 1994·Journal of Child Neurology·E M Mizrahi
Aug 1, 1994·Neuropediatrics·C KuenzleR H Largo
Oct 1, 1994·Acta Paediatrica·M IaiH Niimi
Oct 1, 1994·Pediatric Neurology·Y FujiiM Sudo
Jan 1, 1994·Journal of Child Neurology·J BodensteinerL Cowan
Aug 1, 1995·Neuropediatrics·M A RutherfordL M Dubowitz
Jan 1, 1996·Acta Paediatrica·K Yokochi, S Fujimoto
Nov 1, 1996·Archives of Disease in Childhood. Fetal and Neonatal Edition·M RutherfordL Dubowitz
Aug 1, 1998·Pediatrics·M A RutherfordA D Edwards
Aug 26, 1998·Annals of Neurology·E H RolandA Hill
Jan 26, 1999·Pediatrics·E MercuriL Dubowitz
Aug 30, 2000·Neuropediatrics·L T SieJ Valk
Oct 6, 2000·Pediatric Neurology·S P MillerA M O'Gorman
Mar 7, 2001·Pediatrics·E BiagioniL Dubowitz
Citations
Mar 24, 2009·Pediatric Neurology·Christopher JackmanDeborah K Sokol
Jun 14, 2014·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Ajay BishtBhawani Shankar Sharma
Apr 30, 2015·PloS One·Thomas AlderliestenFloris Groenendaal
Dec 23, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Sachiko KoshinoKei Yamada