Prognostic correlative values of the late-infancy MRI pattern in term infants with perinatal asphyxia

Pediatric Neurology
H TekgülS Tütüncüoğlu

Abstract

The aim of this study was to define the risk ratios of the late-infancy magnetic resonance imaging pattern for long-term outcome in term infants with perinatal asphyxia. We evaluated 65 term infants with perinatal asphyxia and performed magnetic resonance imaging examinations between 4-12 months of age. Magnetic resonance imaging scans were classified as follows: (1) periventricular leukomalacia in 21 (32%) infants, (2) marked cortical atrophy in 17 (26%) infants, (3) multicystic encephalomalacia in 10 (15%) infants, (4) deep gray matter involvement in 8 (12%) infants, (5) focal cortical involvement in 6 (9%) infants, (6) myelination delay in 3 (5%) infants. The overall outcome was favorable in 19 (29%) of 65 infants. Infants with diffuse cortical involvement (multicystic encephalomalacia and marked cortical atrophy) are four times (odds ratio: 4.4 and 4.1 respectively) more likely to attain the unfavorable outcome than the infants with other patterns of magnetic resonance imaging. Infants with focal cortical involvement had relatively favorable outcome in 60% of the cases. In conclusion, it appears that the overall outcome of infants with perinatal asphyxia correlated well with the magnetic resonance imaging patterns obtained ...Continue Reading

References

Aug 1, 1991·Acta paediatrica Scandinavica·K YokochiS Fujimoto
Nov 1, 1990·The Journal of Pediatrics·P ByrneM Piper
Mar 1, 1989·AJR. American Journal of Roentgenology·O FlodmarkM G Norman
Sep 1, 1988·Radiology·L L BakerD R Enzmann
Aug 1, 1995·European Journal of Obstetrics, Gynecology, and Reproductive Biology·H H de Haan, T H Hasaart
Oct 1, 1994·Journal of Child Neurology·E M Mizrahi
Oct 1, 1994·Pediatric Neurology·Y FujiiM Sudo
Jan 1, 1994·Journal of Child Neurology·J BodensteinerL Cowan
Nov 1, 1996·Archives of Disease in Childhood. Fetal and Neonatal Edition·M RutherfordL Dubowitz
Oct 6, 2000·Pediatric Neurology·S P MillerA M O'Gorman

❮ Previous
Next ❯

Citations

Mar 24, 2009·Pediatric Neurology·Christopher JackmanDeborah K Sokol
Jun 14, 2014·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Ajay BishtBhawani Shankar Sharma
Dec 23, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Sachiko KoshinoKei Yamada

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain developing: Influences & Outcomes

This feed focuses on influences that affect the developing brain including genetics, fetal development, prenatal care, and gene-environment interactions. Here is the latest research in this field.

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.