Prognostic criteria in patients with gastrointestinal stromal tumors: a single center experience retrospective analysis.

World Journal of Surgical Oncology
Naoki TanimineHideki Ohdan

Abstract

Gastrointestinal stromal tumors (GISTs) are morphologically and clinically heterogeneous tumors, and their biological behavior is difficult to predict, ranging from clinically benign to malignant. The aim of our study was to reanalyze the value of the commonly used prognostic criteria and recently reported nomogram in predicting disease recurrence in patients with primary resectable GISTs. The clinicopathological features of 60 patients with GISTs who underwent surgical resection between 1998 and 2010 at Hiroshima University Hospital were retrospectively reviewed. Tumors were classified according to the National Institutes of Health and Armed Forces Institute of Pathology criteria, and nomogram predictions were performed. The relationship between patient and tumor characteristics was tested by univariate analysis using the log-rank test. Furthermore, we assessed nomogram performance with the concordance index and calibration. The median patient follow-up was 4.1 years, with 6 of 60 patients experiencing recurrence. Recurrence was observed only in the high-risk group. The recurrence-free survival (RFS) was 93.0 and 89.9% after 2 and 5 years, respectively. The concordance indices of the nomogram prediction were 0.96 and 0.65 for ...Continue Reading

References

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Citations

Apr 4, 2013·International Journal of Surgery Case Reports·Francesco PataAdriana Rotundo
Feb 24, 2015·Surgical Oncology·Jennifer M RaczFayez A Quereshy
Oct 18, 2016·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Vyacheslav BardHanoch Kashtan
Oct 6, 2020·Indian Journal of Surgical Oncology·Kanuj MalikManikandan Dhanushkodi
Feb 13, 2021·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Meng KongLeping Li

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Methods Mentioned

BETA
surgical resection

Software Mentioned

SPSS

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