Prognostic factors for alveolar regeneration: osteogenic potential of resident bone

Journal of Clinical Periodontology
Giuseppe PolimeniUlf M E Wikesjö

Abstract

There is a limited understanding of the role of resident bone in periodontal regeneration. The objective of this study was to evaluate the influence of the resident alveolar bone on bone regeneration in conjunction with guided tissue regeneration (GTR) in the presence or the absence of cell occlusivity. Critical-size, 6-mm, supra-alveolar periodontal defects were created in six young adult Beagle dogs. Space-providing, occlusive or porous expanded polytetrafluaroethylene devices were implanted to provide for GTR. Treatments were alternated between left and right jaw quadrants in subsequent animals. The gingival flaps were advanced for primary intention healing. The animals were euthanized at week 8 postsurgery. The histometric analysis assessed regeneration of alveolar bone relative to space-provision by the GTR device and width of the alveolar crest at the base of the defect. There were no significant differences in mean alveolar regeneration between sites receiving the porous GTR device with a narrow versus a wide alveolar ridge after adjusting for wound area (2.22 versus 2.50 mm, respectively; p=0.36). In contrast, analysis using sites receiving the occlusive GTR device revealed significantly greater bone regeneration at sit...Continue Reading

References

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Jul 2, 2003·Journal of Clinical Periodontology·Ulf M E WikesjöW Ross Hardwick

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Citations

May 12, 2006·Periodontology 2000·Giuseppe PolimeniUlf M E Wikesjö
Feb 25, 2009·Journal of Clinical Periodontology·Giuseppe PolimeniUlf M E Wikesjö
Nov 28, 2007·Clinical Oral Implants Research·Mohammed QahashUlf M E Wikesjö
Jan 10, 2006·Periodontology 2000·Ling Xue KongP Mark Bartold
Feb 3, 2015·Journal of Clinical Periodontology·Liat ChaushuCarlos E Nemcovsky
Feb 16, 2013·Journal of Clinical Periodontology·Hsien-Chung ChiuEarl Fu
Apr 27, 2021·Journal of Clinical Periodontology·Danae A ApatzidouAntonis Konstantinidis

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