Prognostic factors for early gastric cancer in France: Cox regression analysis of 332 cases

World Journal of Surgery
Frédéric BorieFrench Association for Surgical Research

Abstract

Early gastric cancer (EGC) is defined as a lesion in which the depth of invasion is limited to the mucosa, submucosa, or both regardless of lymph node status; moreover, it has an excellent prognosis, with a 5-year survival rate of more than 90%. We aimed to determine the prognostic factors for EGC in a large Western series. Over a 10-year period from January 1979 to December 1988 a series of 332 patients (mean age 64 years) with EGC were operated on in 23 centers (two French Associations for Surgical Research). The clinicopathologic data retrospectively and screened it for prognostic effect. The mean follow-up for the 332 EGC patients was 80 months. Postoperative mortality was 4% among 243 partial and 89 total gastric resections. The overall 5- and 7-year survival rates were 82% and 72%, respectively. The cumulative 5- and 7-year survival rates (mean follow-up 80 months) were 92.0% and 87.5%, respectively, excluding both operative and unrelated mortality. There was no significant difference in survival between partial and total gastric resection for lesions located in the lower third of the stomach ( p > 0.6). When survival data (excluding postoperative deaths) were analyzed using univariate analysis and Cox's proportional haza...Continue Reading

Citations

May 8, 2007·Surgical Endoscopy·E OrsenigoC Staudacher
Sep 8, 2006·Annals of Surgical Oncology·Chikara KunisakiHiroshi Shimada
Nov 29, 2007·Annals of Surgical Oncology·Chen LiSung Hoon Noh
Jul 2, 2009·Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association·Bijan Moghimi-DehkordiMohammad R Zali
Jun 23, 2015·Journal of Gastroenterology and Hepatology·Qingshan PeiXiaoping Zou
Sep 15, 2012·Experimental and Therapeutic Medicine·Baojun HuangHuimian Xu
Apr 26, 2015·International Journal of Surgical Pathology·Mine GulluogluEmre Balik
May 8, 2021·Surgical Oncology·Chikara KunisakiItaru Endo

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